vaccines Flashcards

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1
Q

which vaccines pose a risk to immunocompromised patients

A

Live attenuated

BCG
measles, mumps, rubella (MMR)
influenza (intranasal)
oral rotavirus
oral polio
yellow fever
oral typhoid

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2
Q

Inactivated preparations

A

rabies
hepatitis A
influenza (intramuscular)

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3
Q

Toxoid (inactivated toxin)

A

tetanus

corynebacterium diphtheria

bordettella pertussis

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4
Q

what are Subunit and conjugate vaccines ?

A

Subunit means that only part of the pathogen is used to generate an immunogenic response.

A conjugate vaccine is a particular type that links the poorly immunogenic bacterial polysaccharide outer coats to proteins to make them more immunogenic

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5
Q

Subunit and conjugate vaccines

A

pneumococcus (conjugate)

haemophilus (conjugate)

meningococcus (conjugate)

hepatitis B

human papillomavirus

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6
Q

BCG vaccine does not prevent

A

primary infection with tuberculosis

does not provide reliable protection against any forms of TB in adults

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7
Q

so why is BCG vaccines still used in children once or even sometimes twice ?

A

protective against severe diseases in children, particularly TB meningitis and disseminated TB in children.
preventive in TB meningitis

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