sodium valproate Flashcards
1
Q
adverse effects of sodium valproate ?
A
WEIGHT GAIN
ALOPECIA
HYPONATREMIA
2
Q
if there is Hyperammonemic encephalopathy due to sodium valproate what should be given ?
A
L-carnitine
3
Q
Sodium capitate side effect on gastrointestinal/ Hepato system
A
Hepatotocixity
Pancreatitis
4
Q
Due to possibly the hepatoxicity of sodium valproate what is seen in blood?
A
Thrombocytopenia
5
Q
Neurological features of sodium valproate
A
ataxia / tremor
Hyper ammonia encephalopathy
6
Q
Is sodium validate safe to use in pregnancy?
A
No !
Tetrogenic - neural tube defect
7
Q
Sodium valproate affects an important enzyme in what way
A
P450 INHIBTOR
