Vaccine

Question 1

What is vaccine

Answer 1

A biological preparation intended to stimulate the immune system (produce T cells and produce antibody to B cells)

Question 2

Is polio asymptomatic or symptomatic

Answer 2

Asymptomatic

Question 3

To test polio , Jonas Salk do what

Answer 3

Clinical trials

Question 4

The Salk vaccine is also called

Answer 4

Killed polio vaccine (KPV) or inactivated polio vaccine (IPV)

Question 5

Why there was a small bump of rise in polio case after the vaccine being introduced?

Answer 5

Because there was a manufacturer didn’t follow the procedure to get the completely inactivated virus.

Question 6

Attenuated (Oral) polio vaccine produced by who

Answer 6

Albert Sabin

Question 7

Polio pandemic happens mostly in these two countries

Answer 7

Pakistan and Afghanistan

Question 8

What family does HIV virus belong to

Answer 8

Retrovirus , have RNA as genetic material, not DNA as polio, etc.

Question 9

Characteristics of polio

Answer 9

• Oral transmitted
• Cause muscle waste
• Mostly occur in children.

Question 10

What is the life cycle of the virus? (simple)

Answer 10

• Attachment
• Penetration
• Uncoating
• Biosynthesis
• Assembly
• Release

Question 11

What part of the life cycle virus that polio vaccine targets

Answer 11

• Uncoating (The vaccine will cross link protein, so the virus can’t release their genetic material).

Question 12

There are still two smallpox labs in two places

Answer 12

• CDC (USA)

- Bektop (Russia)

Question 13

What is the most interventions to save children’s lives and keeping adults, community healthy

Answer 13

Vaccines

Question 14

What’s the risk of oral polio vaccine

Answer 14

• Live virus can cause paralytic poliomyelitis.

Question 15

Types of vaccines?

Answer 15

• Attenuated vaccines
• Inactivated vaccines
• Subunit vaccines/DNA vaccines
• Toxoid vaccines

Question 16

What is attenuated vaccines

Answer 16

• Use a weakened form of the virus

smallpox

Question 17

Inactivated vaccines

Answer 17

Use the killed form of virus (Polio, rabies, Hep A)

Question 18

Subunit vaccines

Answer 18

• Use a specific piece of the virus using recombinant DNA technology (express protein outside or inside the host using plasmid)
  (Hep B, HPV)

Question 19

Toxoid vaccines

Answer 19

• Inactivated toxins produce by the germs that help the immune system just targets the toxoid only.
  (diphtheria, tetanus, pertussis)