uworld 11 Flashcards

1
Q

Si/sx of rubella?

A

low grd fever, conjunctivitis, coryza, cervical LAD, head to body spread of blanching maculopapular rash, lasts less than 3 days

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2
Q

Risk fx of endocarditis?

A

Poor dentition, cardiac probs (congenital dx, valvular abnormalities/ repair), IV catheters, IV drug use

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3
Q

Lab/imaging findings w/ infective endocarditis?

A

+ blood cx, leukocytosis or nml WBC, glomerulonephritis signs on UA, septic emboli

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4
Q

What is gold standard for dx of infective endo?

A

TEE is gold std, 100% specific

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5
Q

How tx I.E.?

A

Start w/ vanc, then adjust based on cx

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6
Q

What is alternate test to dx vertebral osteomyelitis?

A

can do bone scan w/ gallium if MRI contraindicated

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7
Q

Causes of constrictive pericarditis?

A

idiopathic or viral pericarditis, cardiac surgery or radiation tx, TB pericarditis

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8
Q

Px of constrictive pericarditis?

A

fatigue + dyspnea, periph edema, JVD, ascites, may hear pericardial knock

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9
Q

JV wave signs of constrictive periccarditis?

A

prominent x and y descents

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10
Q

What are P/E findings of pulmo htn?

A

widely split s2 and incrsd intensity of P2

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11
Q

What is px of polymyositis?

A

slowly progressive prox muscle weakness of lower>upper extrem, cannot get out of chair, climb stairs, muscles of mastication and facial expession typically spared

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12
Q

How best diagnose polymyositis?

A

do muscle biopsy — get mononuclear infiltrate surrounding necrotic and regenerating muscle fibers

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13
Q

when should amiodarone be avoided?

A

Can cause pulm toxicity and should be avoided in pts w/ preexisting lung disease, can cause chronic interstitial pneumonia, organizing pneumonia, ARDS.

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14
Q

How empirically tx patient <50 y/o for meningitis?

A

vanc + 3rd gen cephalosporin

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15
Q

HOw empirically tx >50 y.o w. meningitis?

A

vanc + 3rd gen ceph + ampicillin. If immunocomp use cefepime instead of 3rd gen cephalo

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16
Q

What is INR goal of anticoag after unprovoked DVT?

A

want 2.0-3.0 for 6-12 mo if unprovoked

17
Q

What is INR goal in pt w/ mechanical valve?

A

2.5-3.5

18
Q

Lab findings with tumor lysis syndrome?

A

incrsd uric acid, incrsd PO4 and K, dcrsd Ca

19
Q

Most common cause of hyperPTH?

A

80% due to parathyroid adenoma

20
Q

Other effects of hyperPTH?

A

htn, arrhythmias, ventric hypertrophy, vascular/ valvular calcificiation

21
Q

Causes of exudative pleural effusion?

A

infxn, malignancy, PE, connective tissue dx, iatrogenic

22
Q

when do papillary muscle ruptures occur?

A

classically w/ posteroseptal MIs, can occur rarely w/ anteromedial MIs

23
Q

SI/sx of Guillan Barre syndrome?

A

ascending lower extrem weakness, areflexia, can develop respiratory failure

24
Q

How manage resp failure in GBS?

A

serial VC measurements, risk for resp failure when VC < 15

25
Q

What is ddx for anterior knee pain?

A

patellofemoral syndrome, patellar tendonitis, osgood-schlatter syndrome

26
Q

How diagnose PFS?

A

based on clinical sx, do PF compression test — reproduces pain of squatting

27
Q

How chronic exposure of lead px?

A

same as acute but with fatigue, insomnia, htn, neuropsych sx, nephropathy, reproductive probs

28
Q

Acute exposure of lead posioning sx?

A

ab pain, constipation, HA, periph neuropathy, joint pain, muscle aches, anemia, basophillic stippling, anorexia

29
Q

What can cause cauda equina syndrome?

A

disc herniation, rupture, spinal stenosis, tumors, infxn, hemorrhage, iatrogenic

30
Q

How does conus medullaris px?

A

sudden onset svr back pain, perianal hypo/anesthesia, symmetric motor reflexes, hyperreflexia, bowel and bladder dysfxn

31
Q

What is sympathetic opthalmia?

A

immune mediated inflamm of one eye following injury to other eye, px w/ floating spots and blurred vision in non injured eye.

32
Q

Si/sx of hereditary hemochromatosis?

A

lethargy, fatigue, malaise, skin pigmentation, joint probs/ arthralgia, incrsd LFTs, cirrhosis/ HCC risk, DM, hypogonadotropic hypogonadism, restrictive/dilated HF, cndxn probs

33
Q

Infxns risk for hereditary hemochromatosis?

A

incrsd risk of listeria, vibrio, yersinia

34
Q

Environ risk for pancreatic cancer?

A

smoking greatest, also chronic pancreatitis, obestiy, lack of physical activity

35
Q

How does dipyramidole dx angina?

A

dilates coronary arts distal to obstructed arteies, already max dilated — other vessels dilate and pull blood from obstructed vessels— ischemia

36
Q

How asses signs of adrenal insufficiency?

A

Do cosyntropin test

37
Q

Cosyntropin findings w/ primary adrenal insufficiency?

A

basal cortisol low, ACTH high w/ minimal respons of cortisol to cosyntropin