UTIs to include epididymitis, prostatitis, and pyelonephritis Flashcards
What are among the most common entities encountered in medical practice?
UTIs
What kind of bacteria is responsible for most UTIs?
Coliform Bacteria (E. Coli – most common)
What is the most common route for UTIs?
Ascending infection from the urethra
What is defined as an infection of the bladder?
Acute cystitis
Cystitis is most commonly caused by what?
- E. Coli (coliform bacteria)
2. Enterococci (gram-positive)
True or False
Uncomplicated cystitis in men is rare and implies a pathologic process such as infected stones, prostatitis, or chronic urinary retention requiring further investigation
True
These are all signs and symptoms of what?
- Irritative voiding symptoms
a. frequency
b. urgency
c. dysuria - suprapubic discomfort
- female hematuria/symptoms after sex
- usually afebrile
- may have suprapubic tenderness w/ palpation
Cystitis
These can all be causes of what?
- Pelvic irradiation
- Chemotherapy
- Bladder carcinoma
- Interstitial cystitis
- Voiding dysfunction disorders
- Psychosomatic disorders
Noninfectious cystitis
Lab findings in urinalysis for cystitis may reveal what?
- Pyuria
- Bacteriuria
- Various degrees of hematuria
Since uncomplicated cystitis is rare in men what kind of imaging is warranted?
- Ultrasonography
- Cystoscopy
(or both) - possible CT scan if pyelonephritis, recurrent infections, or autonomic abnormalities suspected
What is the antimicrobial therapy for cystitis?
- Ciprofloxacin (cipro) 250mg q 12hrs, PO 3 days
- Nitrofurantoin (macrobid) 100mg q 12hrs PO 5-7 days
- Trimethoprim/Sulfamethoxazole (bactrim) 160mg TMP PO q 12hrs 3 days
What urinary analgesics can be used for cystitis?
Phenazopyridine (pyridium) 100-200mg q 8hrs as needed PO max 3 days
Women who have more than how many episodes of cystitis per year can be considered for prophylactic antibiotic therapy?
Three episodes per year
What are the three most commonly used oral agents for cystitis prophylaxis?
- Trimethoprim-Sulfamethoxazole (40mg/200mg) daily
- Nitrofurantoin (100mg) daily
- Cephalexin (250mg)
What is an infectious inflammatory disease involving the kidney parenchyma and renal pelvis?
Pyelonephritis
What are the most common causative agents of pyelonephritis?
Gram-negative bacteria
- E coli
- Proteus
- Klebsiella
- Enterobacter
- Pseudomonas
What are some gram-positive bacteria that are less commonly seen in pyelonephritis?
- Enterococcus Faecalis
2. Staphylococcus Aureus
Infection in pyelonephritis usually ascends from the lower urinary tract except what bacteria that is usually spread by a hematogenous route (blood stream)?
S. aureus
These are all signs and symptoms of what?
- Fever
- Flank pain
- Irritative voiding symptoms
- Shaking chills
- Associated nausea and vomiting
- Diarrhea
- Tachycardia
- CVA tenderness is usually pronounced
Pyelonephritis
What are some lab findings for pyelonephritis?
- UA: pyuria, bacteriuria, degrees of hematuria, WBCs
- Urine culture: heavy growth of offending organism
- Blood culture: may be positive
- CBC: Leukocytosis and left shift
What imaging should be done for pyelonephritis?
Renal ultrasound
1. may show hydronephrosis (stone/obstruction)
What antimicrobial therapy is used for INPATIENT treatment of pyelonephritis?
Ampicillin 1g q 6hrs and Gentamicin 1mg/kg q 8hrs IV (14 days)
What antimicrobial therapy is used for OUTPATIENT treatment of pyelonephritis?
- Ciprofloxacin (Cipro) 750mg q 12hrs PO (7-14 days)
2. Levofloxacin 750mg PO (7-14 days)