Cervical Dysplasia Flashcards
What starts in puberty because of hormonal influence and changes in the vaginal pH, the tissue of the cervix can undergo cellular changes?
Cervical dysplasia
Infection with ___ may lead to cellular abnormalities and over a period of time, this can develop into cervical dysplasia or cancer
HPV
There are varying degrees of dysplasia also known as what?
Neoplasia
True or False
All atypia (presence of abnormal cells) must be observed and treated if persistent or worsening
True
Cervical dysplasia is defined by the degree of what?
Cellular atypia
Cervical dysplasia is also called what?
Cervical Intraepithelial Neoplasia (CIN)
Are there specific symptoms or signs of cervical dysplasia?
No, patients are often asymptomatic
A presumptive diagnosis of cervical dysplasia is made by what abnormal test of an asymptomatic woman with no grossly visible cervical changes?
PAP smear
True or False
All visible abnormal cervical lesions should be referred to OB/GYN for biopsy and possible therapy
True
In immunocompetent women, cervical cancer screening should begin at what age, regardless of the age of onset of sexual intercourse?
21 y/o
The US Preventive Services Task Force (USPSTF) recommends screening for cervical cancer in women aged 21 to 65 years with cytology (PAP smear) every ____ years or for women aged 30 to 65 years, screening with a combination of cytology and HPV testing every__ years. Assuming negative HPV risk factors.
- 3 years
2. 5 years
The USPSTF recommends against screening for cervical cancer with HPV testing, alone or in combination with cytology, in women younger than age ____. HPV can “go away’ in younger women.
30 years old
The USPSTF also recommends against cervical cancer screening for women older than age ____ who have had adequate prior screening and are not otherwise at high risk or cervical cancer.
65 years old
In cervical dysplasia, pap smear findings can be described in one of several ways using the Bethesda system, such as what?
- Atypical squamous cells of unknown significance (ASC-US)
- Squamous intraepithelial lesions (SIL)
a. Low-grade (LSIL)
b. High-grade (HSIL
What is a diagnostic procedure in which a colposcope (a dissecting microscope with various magnification lenses) is used to provide an illuminated, magnified view of the cervix, vagina, vulva, or anus?
Colposcopy
Women with ASC-US and a negative HPV infection screening may be followed up in ___ year for a repeat Pap smear and HPV co-testing?
1 year
Is a colposcopy indicated if the HPV screen is positive?
Yes
True or False
All patients with SIL or atypical glandular cells should undergo colposcopy
True
True or False
Cervical dysplasia
Colposcopically directed punch biopsy and endocervical curettage is necessary for diagnosis and planning of treatment
True
Cervical infection with what is associated with a high percentage of all cervical dysplasia and cancers?
HPV
What vaccination can prevent cervical, vaginal, and vulvar cancers and low grade and precancerous lesions caused by HPV, and is recommended for females and males aged 9 and older?
Gardasil
All treatments for cervical dysplasia are performed by OB/GYN but varies on the degree and extent of CIN, but what should precede the treatment?
Biopsies (except in cases of HSIL)
What treatment for cervical dysplasia is effective for noninvasive small lesions visible on the cervix?
Cryosurgery
In cases of HSIL it may be appropriate to proceed directly to what?
Loop electrosurgical excision procedure (LEEP) (wire loop is used for excision)
What treatment is reserved for cases of severe dysplasia or cancer?
Conization of the cervix
True or False
ALL patients with an abnormal PAP smear findings should be referred to physician supervisor or OB/GYN for further evaluation
True
