Ovarian Mass

Question 1

True or False

Ovarian tumors are common but most are malignant

Answer 1

False

Most are benign

Question 2

What are the leading cause of death from reproductive tract cancer?

Answer 2

Malignant ovarian tumors

Question 3

Women who carry what gene mutation have an increased risk for ovarian cancer?

Answer 3

BRCA

Question 4

Most women with both benign and malignant ovarian neoplasms are either symptomatic or experience only mild symptoms like what?

Answer 4

1. Mild nonspecific GI symptoms

2. Pelvic pressure

Question 5

Ovarian Mass

Women with advanced malignant disease may experience what kind of symptoms?

Answer 5

1. abdominal pain
2. bloating
3. palpable abdominal mass with ascites is common

Question 6

What are some labs that should be done for a patient with an ovarian mass?

Answer 6

1. Tumor markers (serum)
   a. cancer antigen 125
   b. HCG
   c. Lactate dehydrogenase
   d. Alpha fetoprotein

Question 7

What imaging is helpful in differentiating ovarian masses that are benign and those with malignant potential? (solid vs cystic is important)

Answer 7

Transvaginal ultrasound

Question 8

What kind of imaging helps further enhance specificity of a possible ovarian mass?

Answer 8

Color Doppler

Question 9

What is the treatment for a malignant ovarian mass?

Answer 9

1. surgical evaluation and staging by gynecologic oncologist
2. combinations of hysterectomy and bilateral salpingooophorectomy with omentectomy and selective lymphadenectomy
3. postoperative chemotherapy or watchful waiting

Question 10

Ovarian mass

What is the treatment for benign neoplasms?

Answer 10

Tumor removal or unilateral oophorectomy

Question 11

Ovarian cancer is usually diagnosed after advanced disease is present in about what percentage of the time?

Answer 11

75% of the time

Question 12

Ovarian mass

What is the 5-year survival rates for the following?

1. Early disease___
2. Local spread___
3. Distant metastases___

Answer 12

1. 89%
2. 26%
3. 17%