UTIs & SSTIs

Question 1

What medications are indicated in uncomplicated UTIs?

Answer 1

nitrofurantoin, fosfomycin
cefpodoxime, cefadroxil, cephalexin, augmentin
smx/tmp
cipro, levo

Question 2

What medications are indicated in complicated/inpatient UTIs?

Answer 2

ampicillin + gentamicin
ampicillin +/- cefazolin
ceftriaxone
piperacillin/tazobactam
cefepime
gentamicin

Question 3

What medications are indicated for prostatitis?

Answer 3

ciprofloxacin/levofloxacin
smx/tmp
maybe cephalexin, augmentin

Question 4

what medications are indicated for mild non-purulent SSTI?

Answer 4

penicillin VK, cephalopsporin, clindamycin

Question 5

what medications are indicated for moderate non-purulent SSTI?

Answer 5

IV pencillin, ceftriaxone, cefazolin, clindamycin

Question 6

what medications are indicated for severe non-purulent SSTI?

Answer 6

vancomycin + piperacillin/tazobactam

Question 7

What medications are indicated for mild purulent SSTI?

Answer 7

none!
just incidison and drainage

Question 8

what medications are indicated for moderate purulent SSTI?

Answer 8

doxycycline or tmp/smx
if MSSA cephalexin

Question 9

what medications are indicated for severe purulent SSTI?

Answer 9

vancomycin or daptomycin or linezolid
if MSSA nafcillin, cefazolin, clindamycin

Question 10

What IV antibiotics are indicated for necrotizing fasciitis?

Answer 10

vancomycin + piperacillin/tazobactam
if S. Pyogenes then penicillin + clindamycin

Question 11

What medications are indicated in a mild diabetic foot infection?

Answer 11

cephalexin, clindamycin x 1-2 weeks
if recent antibiotics –> amoxicillin/clavulanate
if MRSA risk –> smx/tmp, doxycycline

Question 12

what medications are indicated in a moderate diabetic foot infection?

Answer 12

moxifloxacin
amoxicillin/clavulanate
ciprofloxacin/levofloxacin + metronidazole or clindamycin x 2-3 weeks

if pseduomonas risk –> ciprofloxacin/levofloxacin + metronidazole or clindamycin

if MRSA risk –> ADD doxycycline, linezolid, vancomycin, smx/tmp

Question 13

what medications are indicated in a severe diabetic foot infection?

Answer 13

piperacillin/tazobactam, carbapenem, cefepime + clindamycin or metronidazole x 2-3 weeks

if MRSA risk –> vancomycin, linezolid, daptomycin

Question 14

What medications are indicated in animal/human bites?

Answer 14

amoxicillin/clavulanate
alt. 2nd or 3rd generation cephalopsporin (cefpodoxime, cefuroxime) + anaerobic coverage

Question 15

what medications are indicated in impetigo?

Answer 15

if mild then mupropicin
if severe then pencillin x 1 week
or doxycycline, clindamycin, tmp/smx