Bacteremia, Endocarditis, C.Diff & IAI

Question 1

What is the treatment of choice for endocarditis positive for viridans group streptococci or S. gallolyticus?

Answer 1

Pen G or ceftriaxone +/- gentamicin
vancomycin if pen allergic

Question 2

what is the treatment for MSSA endocarditis NVE?

Answer 2

nafcillin/oxacillin x 6 weeks
cefazolin if pen-allergic

Question 3

what is the treatment for MRSA endocarditis NVE?

Answer 3

vancomycin or daptomycin

Question 4

what is the treatment for MSSA PVE?

Answer 4

nafcillin/oxacillin + rifampin + gentamicin

Question 5

What is the treatment for MRSA PVE?

Answer 5

vancomycin + rifampin + gentamicin

Question 6

what is the treatment for enterococci for NVE/PVE?

Answer 6

ampicillin + gentamicin
pencillin + gentamicin
ampicillin + ceftriaxone for renal insufficiency

Question 7

What is the treatment of HACEK organisms for PVE/NVE?

Answer 7

ceftriaxone
ampicillin +/- sulbactam
cipro if pen allergic

Question 8

What is the empiric treatment recommendations for SBP?

Answer 8

ceftriaxone, cefepime, meropenem, piperacillin/tazobactam
+ MSRA coverage (vanc, dapto, linezolid)

Question 9

What do you not want to use in intra-abdominal infections?

Answer 9

ampicillin/sulbactam

Question 10

What are some common medications used for mild/moderate IAIs?

Answer 10

ceftriaxone, cefazolin, cefoxitin, ertapenem, tigecycline

Question 11

What are some common medications used for severe IAIs?

Answer 11

piperacillin/tazobactam
meropenem
cefepime