UTIs Flashcards
What is lower UTI?
Bladder (cystitis)
Prostate (prostatitis)
What is Upper UTI?
Kidneys (pyelonephritis)
What are the predisposing factors to UTI?
Short urethra in females
Sexual activity
Urinary incontinence
Oestrogen deficiency in menopause
Dehydration
Obstruction e.g. kidney stones
Diabetes
Immunosuppression
Pregnancy
Catheterisation
Renal tract malformation
What are the most common bacteria in UTI?
E.coli (75-95%)
Staphylococcus saprophyticus (5-10%)
Klebsiella pneumoniae
Proteus mirabilis
What are the symptoms of cystitis?
Frequency
Dysuria
Urgency
Suprapubic pain
Polyuria
Haematuria
Cloudy or foul smelling urine
What are the symptoms of prostatitis?
Pelvic pain
Urinary symptoms- dysuria, hesitancy, frequency, retention
Swollen or tender prostate
Sexual dysfunction
Pain with bowel movements
Systemic- fever, myalgia, nausea, fatigue
What are the symptoms of pyelonephritis?
Fever
Rigor
Vomiting
Loin/back pain
Sepsis
What is the pathology of pyelonephritis?
Affects tubules, interstitium and renal pelvis
Interstitial abscesses filled with pus
Tubules damaged, contain neutrophil casts
What is chronic pyelonephritis?
Repeated episodes of acute
Leads to fibrosis, renal interstitium scarring and renal tubules atrophy
What investigations are done for UTI?
Urine dipstick- non pregnant women
MSU culture- pregnant women, men, children
Blood tests- systemically unwell
Imaging, men with upper UTI, a recurrent UTI, failure to respond to treatment, pyelonephritis
What is present on urine dipstick in UTI?
Nitrites
Leukocytes
RBCs
What is the management of a non pregnant woman with 3+ symptoms of cystitis and no vaginal discharge?
3 day course of trimethoprim or nitrofurantoin (if eGFR>30)
What is the management of a non pregnant immunosuppressed woman with UTI?
5-10 days of antibiotics
What is the management of a non pregnant with upper UTI?
Urine culture and treat with broad spectrum antibiotic e.g. co-amoxiclav
What is the management of a UTI in a pregnant woman?
Get expert help
Treat with antibiotic for 7 days- nitrofurantoin, amoxicillin
Confirm eradication