Uterine and Ov Pathology Flashcards
adenomyosis
benign invasive growth of endo into the myometrium
asherman syndrome
IU adhesions ablating the endo lining
gartner dust cyst
small cyst w/in vag
hematocolpos
blood accumulation in vag
hematometra
blood accumulation in the ut
hematometrocolpos
blood accumulation in the ut and vag
hyperplasia
proliferation of the endo lining
intramural leiomyoma
mass distorting the myo, most common location
leiomyoma
most common benign gynecological tumor of the myo
meigs syndrome
combination of pleural effusion, ascites, and an ov mass that resolve after surgery
submucosal leiomyoma
mass distorting the endo, least common but most likely to cause symptoms
subserosal leiomyoma
mass found on the serosal surface of the UT
tamoxifen
antiestrogen medication used to treast breast cancer
tip of the iceberg
term used to describe the sono appearance of dense ov dermoid tumor
cystic terotima (dermoid)
most common primary ov neoplasm
adenomyosis
ectopic endo tissue within the myo
adenomyosis risk factors
multiparity
elevated estrogen
aggressive curettage
adenomyosis clinical findings
pelvic pain/ cramping
UT enlargement and tenderness
menorrhagia
dysmenorrhea
adenomyosis sono findings
diffuse ut enlargement inhomogeneous myo poorly defined anechoic are w/in myo posterior ut wall affected endo appears normal
Leiomyoma (fibroid)
Intramural
distorts myo
confined to myo
most common
Leiomyoma
Pedunculated
attached to the ut by stalk
appears extrauterine
Leiomyoma
Submucosal
distorts the endo
impedes endo
most symptomatic
Leiomyoma
Subserosal
located under perimetrium
distorts ut contour
Leiomyoma clinical findings
asymptomatic menorrhagia pelvic pain ut enlargement irregular bleeding urinate frequently infertility
Leiomyoma sono findings
well defined hypo ut mass anechoic to hyperechoic heterogenous with necorsis or hemorrhage often mutliple increase in size w/ estrogen stimulation decrease after menopause
leiomyosarcoma
derived from the smooth muscle of the ut
rare
leiomyosarcoma clinical findings
asymptomatic
vag bleeding
leiomyosarcoma sono findings
heterogeneous ut mass
irregular margins
Carcinoma of the cx
epithelial neoplasm
carcinoma of cx risk factors
- early sexual activity
- multiple sex partners
- use of oral contraceptive
- smoking
- 3rd most common gyn malignancy in US
Carcinoma of cx sono appearence
- hypoechoic to heterogeneous retrovescial mass
- irregular margins
- dilated ureter
- anechoic or hypoechoic endo fluid collection
Nabothian cyst
cyst in the cx
Nabothian cyst sono appearence
- round, anechoic
- ## multiple or solitary
hyperplasia sono findings
- thickening of endo
- premenopausal: >14 mm
- postmenopausal: >5 mm w/ symptomatic, > 8 mm w/ asymptomatic
Polyp
- overgrowth of endo tissue
- unresponsive to progesterone
polyp sono findings
- focal area of echogenic endo thickening
- color may demonstrate flow w.in stalk
Follicular cysts of ov
graafin follicle which fails to ovulate and enlarges
If cyst contains blood its termed
hemorrhagic cyst
Corpus Luteum cyst normally regress if
fertilization does not take place
corpus albicans
s small echogenic structure that occurs when corpus luteum regressed
If corpus luteum cyst gets to large, ov can
torsion
Corpus Luteum normally resolves around
16 w
Hemorrhagic cyst sono findings
variable appearance including complex components or entirely echogenic depending on amount of blood and stage
Theca Lutein cyst
- largest and least common functional cyst
- found in elevation of hCG
Common conurrent conditions for theca lutein cyst
gestational trophoblastic disease and ovarian hyperstimulation syndrome
Theca lutein cyst regress after
high level of hCG diminishes
Paraovarian cyst located
adjacent to ov but not attached
Cystic teratoma - dermoid results from
retention of unfertilized ovum that differentiates into the three germ cell layers ( ectoderm, mesoderm, and endoderm)
Because of the combination of germ cell layers, dermoids contain
glandular thyroid components, bone, hair, sebum, fat, cartilage, and digestive elements
Asherman Syndrome Clinical Findings
- asymptomatic
- amenorrhea
- dysmenorrhea
- hypomenorrhea
- infertility
Asherman Sono Findings
- inability to distinguish endo cavity
- bright echoes w/in echo
Carcinoma of endo is assoc with
estrogen stimulation
Most common carcinoma of endo
adenocarcinoma
Carcinoma of endo risk factors
- obesity
- diabetes
- nulliparity
- postmenopausal
Carcinoma of endo clinical findings
abnormal bleeding
Carcinoma of endo sono findings
- focal irregularity of endo
- myo distortion
- thick endo
- compless endo mass
Endometriosis
- PID
- retained products of conception
- postprocedural complication
- vaginitis
endometriosis clinical findings
- pelvic pain
- fever
- leukocytosis
endometritis sono findings
- thick and irregular endo
- pronounced endo
- enlarged, inhomogeneous ut
- hypervascular endo and myo
hematometra
- imperforated hymen
- cx stenosis
- vag neoplasm
hematometra clinical findings
- pelvic pain
- amenorrhea
- hypomenorrhea
- pelvic mass
hematometra sono findings
- large hypo midline ut mass
- posterior enhancement
- minimal or lack of visible myo tissue
Tamoxifen clinical findings
- asymptomatic
- abnormal bleeding
tamoxifen sono findings
- normal appearing endo
- thickening of endo
- complex appearence of endo cavity
Cystadenocarcinoma
epithelial neoplasm
cystadenocarcinoma clinical findings
- palpable pelvic mass
- unexplained weight gain
- pelvic pain
cystadenocarcinoma sono findings
- multilocular complex mass
- ill defined wall margins
- mural nodules
- ascites
cystic teratoma sono findings
- “tip of an iceberg”
- complex mass
- thick irregular mass
- calcifications
- commonly located superior to ut fundus
cystic teratoma clinical findings
- asymptomatic
- abd pressure
- mid to acute pelvic pain
- palpable pelvic mass
mucinous cystadenoma clinical findings
- pelvic pain
- rapid increase in pelvic mass
- irregular menses
- bloating
mucinous cystadenoma sono findings
- multilocular anechoic mass
- thick smooth wall margins
- may contain debris
- generally unilateral
PCOS
- endocrine imbalance causing chronic anovulation
- imbalance of LH and FSH
PCOS clinical findings
- irregular menses
- hirsutism
- infertility
- obesity
PCOS sono findings
- round enlarged ov
- presence of ten or more follicles per ov
- multiple small peripheral cysts
serous cystadenoma
- epithelial neoplasm
- second most common benign tumor of ov
serous cystadenoma sono findings
- large unilocualr or multilocular anechoic mass
- smooth thin walled margins
- may contain internal debris and septae
- unilateral
serous cystadenoma clinical findings
- rapid increase of pelvic mass
- pelvic pain
- irregular menses
- bloating
Surface epithelial cyst
arise form cortex of ov
surface epithelial cyst clinical findings
- asymptomatic
- pelvic pain
surface epithelial cyst sono findings
small cluster of cyst
theca lutein cyst is assoc with
high levels of hCG
theca lutein cyst clinical findings
- asymptomatic
- hyperemesis
- abd bloating
theca lutein cyst sono findings
- multilocular cystic structure
- bilateral
theca lutein cyst
- gestational trophoblastic disease
- hyperstimulation syndrome
Brenner tumor
- benign tumor arising from fibroepithelial tissue
- estrogenic in nature
- assoc with meigs syndrome
Brenner tumor clinical findings
- asymptomatic
- unilateral pelvic pain or fullness
brenner tumor sono findings
- small hypo solid ov mass
- well defined wall margins
- does not demonstrate posterior acoustic enhancement
- may demonstrate necrosis
carcinoma of ov
epithelial or germ cell neoplasm
carcinoma of ov risk factors
- high fat diet
- infertility
- nulliparity
- family hx of breast or ov carcinoma
carcinoma of ov clinical findings
- asymptomatic
- vague abd pain
- palpable pelvic mass
- elevated CA125
- vague GI symptoms
- bloating
carcinoma sono findings
- predominately solid hypo ov mass
- irregular ov margins
- may appear complex
- internal blood flow
- resistive index > 1 suggest malignancy
dysgerminoma
- malignant germ cells neoplasm
- most common ov malignancy in childhood
dysgerminoma clinical findings
- asymptomatic
- precocious puberty
- pelvic pain
- palpable pelvic mass
- assoc with AFP adn hCG levels
- spread to lymphatics
fibroma
rare benign stromal tumor
fibroma clinical findings
- asymptomatic
- pelvic pain
- urinary or intestinal disturbance
- menopause
fibroma sono findings
- solid hypo adnexal mass
- dense mass
- may demonstrate posterior shadowing
- ascities
- 5-10 cm
- unilateral
granulosa cell tumor
hormonal tumor
granulosa cell tumor clinical findings
- increase in estrogen
- palpable mass
- irregular bleeding
granulosa cell tumor sono findings
- solid homo adnexal mass
- complex
- thickening of endo
thecoma
- benign stromal tumor
- produces estrogen
thecoma clinical findings
- pelvic pain or pressure
- menopause
thecoma sono findings
- hypo mass
- prominent posterior shadowing
Arteriovenous fistula
- vascular plexus of arteries and veins w/o intervening capillary network
- pelvic surgery
- pelvic trauma
- gestational trophoblastic disease
- malignancy
Arteriovenous fistula clinical findings
- menorrhagia
- amenia
- often diagnosded postabortion and postpartum
Arteriovenous fistula sono findings
- multiple serpingous anechoic structures w/in myo
- abundant blood flow within the anechoic structure
- intramural mass
- moasiac pattern on doppler
- flow reversal and areas of aliasing
- high- velocity, low resistance arterial flow coupled w/ high velocity venous flow w/ arterial component on spectral analysis
Ov Torsion
- partial or complete rotation of oc on its pedicle
- commonly assoc w/ adnexal mass
ov torsion clinical findings
- severe or consistent pelvic pain
- nausea/vomiting
- palpable pelvic mass
ov torsion sono findings
- decreased or absent venous and arterial blood flow to the ov
- large hetero ov mass
- free fluid
- coexisting adnexal mass