Urinary System Flashcards

1
Q

What is excreted in urine

A

Urea
Uric Acid
Creatinine
-

Nitrogen (H+)
Medication / Toxins

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2
Q

Minimum urine excrete per day

A

500mL

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3
Q

Important electrolytes balanced by Kidney

A

Sodium, Potassium, Hydrogen

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4
Q

Two main hormones created by Kidney

A

Calcitriol

Erythropoietin

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5
Q

Calcitriol function

A
  1. Stimulates calcium & magnesium uptake from GIT

2. Reduces calcium loss in Kidney

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6
Q

Erythropoietin function

A

stimulates erythropoiesis in red bone marrow

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7
Q

Renal threshold for glucose is

A

9mmol/L

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8
Q

The kidneys control blood pressure and volume by;

A

Conserving or eliminating water.

Blood pressure is regulated by the release of Renin from kidneys

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9
Q

Pathway triggered by release of an enzyme from the kidney to control blood pressure:

A

Renin-Angiotensin-Aldosterone pathway

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10
Q

Layers of Kidney

A
Renal Capsule (deep)
Adipose capsule (middle)
Renal Fascia (superficial)
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11
Q

Layers of ureters

A

Inner mucous membrane
Muscularis - smooth muscle
Adventitia - outer coat connective tissue

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12
Q

Small triangular area in back of bladder

A

trigone

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13
Q

Two sphincters of urethra

A

Internal Urethral Sphicter (involuntary)

External Urethral Sphincter (Voluntary)

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14
Q

Male Urethra passes through

A

Prostate

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15
Q

Three stages of Urine formation

A
  1. Glomerular filtration
  2. Tubular reabsorption
  3. Tubular secretion
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16
Q

What substances pass through glomerulus ?

A

Water, elecrolytes, amino acids, glucose, hormones, ketoacids, creatinine, urea, uric acid, toxins

17
Q

Which substances do not pass through the glomelerus ?

A

Blood cells, plasma proteins, platelets

18
Q

What is the GFR

A

Glomerular Filtration Rate - the amount of filtrate formed in the renal cropuscle of both kidneys each minute

19
Q

Normal GRF

A

90ml/min

20
Q

What happens when Albumin leaks into urine

A

Loss of osmotic pressure within the blood - resulting in oedema.

21
Q

Where is reabsoption occuring

A

Mainly in Proximal Convoluted Tubule

Water, amino acids, glucose, electrolyes

22
Q

Hormones that affect kidney reabsorption of sodium, chloride, calcium & water

A
Angiotensis 2
Aldosterone
Antidiuretic hormone
Atrial natriuretic peptide
parathyroid hormone
23
Q

What does the RAAS Do?

A

Increases blood pressure

24
Q

Basic RAAS pathway

A

Kidneys: Release enzyme Renin

Liver: Renin converts angiotensinogen to angiotenisin

Lungs: Angiotensin 1 is conversted into Angiotensin 2 by an enzyme called ACE

Adrenal Cortex: Angiotensin 2 causes the release of Aldosterone

25
Q

What does Angiotensin 2 do

A
  1. triggers pituitary gland to release ADH

2. Stimulates Adrenal Cortex to release Aldosterone

26
Q

What does Aldosterone do?

A

Increases renal absorption of water and sodium

27
Q

What affect does Parathyroid hormone have on the Kidneys

A

Stimulates release of calcitriol.

It causes the kidney to reabsorb calcium and magnesium.