URINARY SYSTEM Flashcards
what is urology
medical specialty that focuses on the urinary system and its disorders and also include male and female reproductive system
what does the urinary system consist of
2 kidneys
2 ureters
bladder and urethra
What is the urinary system linked to
reproductive system- in many animals the egg and sperm are emitted through the urinary tract
in humans males, sperm are emitted through the urethra
what are the functions of kidneys
- excretion of wastes- filter blood plasma and separate wastes whilst returning useful substances back to bloodstream
- regulation of blood volume and pressure by water conservation/ elimination
- regulation of osmolarity of body fluids
- secretion of enzyme renin for regulation of BP and electrolytes
- secretion of hormone erythropoietin that stimulates RBC production
- regulation of pCO2 and acid base balance of body fluids
- synthesis of hormone calcitrol for calcium homeostasis
- glucosegenesis in conditions of extreme starvation
what is waste
any substance that is useless to the body or present in excess of need
what is metabolic waste
waste produced by the body; faeces is not a metabolic waste
what is nitrogenous waste
among the toxic of metabolic wastes; 50% is urea produces by protein catabolism
what is excretion
process of separation wastes from the body fluids and elimination them
what is excretion carried out by
- respiratory system- C02, water
- integumentary system- water, inorganic salts, lactic acid and urea in sweat
- digestive system- not only eliminates food residue (not excretion) but excretes water, salts, CO2, lipids, bile pigments, cholesterol and other metabolic wastes
- urinary system- broad variety of metabolic wastes, toxins, drugs, hormones, salts, hydrogen ions and water
gross anatomy of kidneys
0.4% body weight but 21% of cardiac output
what is renal circulation
the larger blood vessels of the kidney
what is a nephron
functional unit of kidney
how many nephrons does the kidney have
1.2 millions
what is the nephron composed of
2 parts; renal corpuscle that filters the blood plasma and renal tubule that converts the filtrate into urine
which nephron has short loops
cortical nephrons
which nephron has long loops
juxtamedullary nephrons- responsible for conservation of water
what is the renal corpuscle
glomerulus + glomerular casule
where does the blood flow through
afferent arteriole
formation of urine
- glomerular filtration
- tubular reabsorption
- water conservation
what is glomerular filtration
creates a plasmalike filtrate of the blood
what is tubular reabsorption
removes useful solutes from the filtrate, returns them to the blood and tubular secretion removes additional wastes from the blood, adds them to the filtrate
what is water conservation
removes water from the urine and returns it to blood; concentrates wastes
what is glomerular filtration rate
amount of filtrate produced per minute by the two kidneys
what is the GFR in males and females
M: 125ml/min; 180l/day
F: 105ml/min; 150l/day
tubular reabsorption/ secretion
- PCT reabsorbs 65% of glomerular filtrate; PCT accounts for 6% of resting ATP usage- active transport
- PCT reabsorbs
i. sodium, potassium, magnesium, phosphate- 65%
ii. glucose- 100%
iii. urea- 40-60%
iv. water- 67% - secretion in PCT and loop
i. nitrogenous wastes, bile acids, catecholamines, prostaglandin
ii. drugs- morphine, aspirin, penicillin
iii. hydrogen and bicarbonate ions to regulate pH - Loop reabsorbs 25% of sodium, potassium and chloride, 15% of water
- fluids arriving at the DCT contains 20% of the water & 7% of the salts from the glomerular filtrate
what is water conservation
- the nephron loops generate a large concentration gradient in the renal medulla
- water is reabsorbed by osmosis from the collecting ducts
- longer loops can generate greater concentration gradients= greater ability to concentrate urine eg desert animals