Urinary System Flashcards

1
Q

What are the layers of the kidney

A

Cortex
Medulla
Pelvis

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2
Q

What is in the renal cortex

A

Glomeruli
PCT
DCT

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3
Q

What is a medullary ray

A

A collection of loop of Henle’s and collecting ducts that originate from the nephrons that have the renal corpuscle in the outer part of the cortex

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4
Q

Are there glomeruli in the renal medulla

A

No

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5
Q

What is the glomerulus supported by

A

Mesangial cells

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6
Q

What’s surrounds the glomerulus

A

Bowmans capsule

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7
Q

What is the basement membrane of the glomerulus lined by

A

Podocytes

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8
Q

What stain highlights the glomerular basement membrane

A

Periodic acid shciff

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9
Q

What do mesangial cells comprise

A

Smooth muscle

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10
Q

 Does albumin get filtrated out of the capillary lumen

A

No it’s too large

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11
Q

What is specific about the basement membrane of the glamorous

A

It’s a double basement membrane and it’s negatively charged

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12
Q

Where is the juxtaglomerular apparatus

A

Right next to the glomerulus

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13
Q

What do granular cells do

A

Detect blood pressure and secrete renin at low blood pressures

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14
Q

What does the juxtaglomerular apparatus contain

A

Granular cells and macula densa cells

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15
Q

What is glomerular tubular feedback

A

Where the macula densa cells detect sodium concentrations and feedback to the afferent arteriole

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16
Q

What is the proximal convoluted tubule lined by

A

Simple cuboidal epithelium

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17
Q

What is the border of proximal convoluted tubule cells

A

A prominent brush border of microvilli

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18
Q

What does the proximal convoluted tubule reabsorb

A

2/3 of the sodium and potassium

19
Q

What is the histological difference between the thick and thin limb of the loop of Henle

A

Thin - simple squamous

Thick - cuboidal

20
Q

How can you recognise the distal convoluted tubule

A

There’s no microvilli and therefore no prominent brush border

21
Q

How does the distal convoluted tubule regulate acid base balance

A

It’s a secretes H+ and absorbs bicarbonate

22
Q

How does the distal convoluted tubule regulate sodium

A

Exchanges sodium for potassium via aldosterone

23
Q

What do the principle cells respond to

A

Aldosterone and ADH

24
Q

How does ADH increase water reabsorption

A

Increases aquaporin 2 channels in the apical membrane

25
Q

What do the intercalated cells do

A

Alpha cells secrete hydrogen ions and beta cells secrete by bicarbonate

26
Q

What level does the renal artery come off the abdominal aorta

A

L1

27
Q

What are the divisions of the renal artery

A
Anterior and Posterior
Interlobar 
Arcuate 
Interlobular
Afferent arteriole
28
Q

What is the renal pelvis lined by

A

Urothelium

29
Q

What does the renal pelvis do

A

Transports filtrate from nephron to ureter

30
Q

What is urothelium

A

A stratified epithelium that can stretch in 3 dimensions

31
Q

What cells are on the surface of urothelium

A

Umbrella cells

32
Q

How do umbrella cells prevent the passage of urine between them

A

They have tight intercellular junctions

33
Q

What is underneath the umbrella cells in the urothelium

A

Pseudostratified layer of polygonal cells

34
Q

What are the layers of muscle in the ureters

A

Inner longitudinal and outer circular

35
Q

What is the bladder lined by

A

Urothelium

36
Q

What creates a functional valve in the bladder

A

The world to find muscularis propria which the Ureta has to pass through to get to the bladder

37
Q

What is the proximal female urethra lined by

A

Transitional epithelium

38
Q

What is the distal female urethra lined by

A

Squamous epithelium

39
Q

What glands open to the female urethra

A

Paraurethral and periurethral

40
Q

What are the parts of the male urethra

A

Prostatic urethra
Membranous urethra
Penile urethra

41
Q

What is the prostatic urethra line by

A

Urothelium

42
Q

What is the membranous urethra lined by

A

Urothelium

43
Q

What is the proximal penile urethra lined by

A

Pseudostratified epithelium

44
Q

What is the distal penile urethra lined by

A

Stratified squamous epithelium