Urinary Bladder Flashcards

1
Q

Patent urachus/urachal cyst think:

A

adenocarcinoma

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2
Q

Recurrent pyelonephritis think:

A

Vesicoureteral reflux

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3
Q

Diverticula increase risk for:

A

stasis –>

infection

calculi

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4
Q

Common cause of cystic (bladder) diverticula?

A

bladder outlet obstruction

ie. BPH, neoplasm

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5
Q

Failure of development of anterior abdominal wall:

A

Exstrophy

incr. risk of chronic infx, adenocarcinoma

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6
Q

Tissue character in adenocarcinoma?

A

glandular, mucous secreting

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7
Q

Conditions predisposing to bladder inflammation:

A

anything that causes stasis:

extrophy

obstruction

fistula

catheters

cystocele (multiple pregnancies)

calculi

neoplasms

Diabetes (bugs like sugar)

pyelo

pregnancy

neurogenic bladder

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8
Q

common presentation of bladder infx in old people?

A

altered mental status

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9
Q

Triad of sx for cystitis:

A

frequency

pain

dysuria

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10
Q

Cause of cystitis in immunosupressed?

A

candida

cryptococcus

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11
Q

Cause of cystitis in young sexually active pts:

A

chlamydia

mycoplasma

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12
Q

Most common causes of cystitis:

A

bacteria

E. coli

Proteus

Enterococcus

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13
Q

non-infx causes of cystitis:

A

radiation

chemo
-cyclophosphamide– HEMORRHAGIC

Hunner ulcer

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14
Q

PAINFUL

autoimmune related (SLE)

CULTURE NEGATIVE

cystitis

A

Hunner ulcer (interstitial)

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15
Q

Histo of acute cystitis:

A

PMNs

exudate

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16
Q

Histo of chronic cystitis?

A

LYMPHOCYTES

epithelial hyperplasia

fibrosis

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17
Q

soft, yellow raised plaques

Michaelis-Gutman bodies

E. coli, Proteus

foamy macrophages

A

Malacoplakia

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18
Q

Most common bladder neoplasm:

A

Transitional cell carcinoma (uroepithilial)

19
Q

Prognosis for “sea anemone” appearing tumors:

A

good

20
Q

Prognosis for cauliflower appearing tumors:

A

bad

21
Q

Environmental toxin associated with bladder cancer in workers?

A

Aniline dye

22
Q

High suspicion for bladder CA with this exam finding:

A

Gross, painless hematuria

23
Q

Gross, painless hematuria in pt over 40:

A

bladder CA until proven otherwise

24
Q

RBC casts present on UA indicate:

A

kidney etiology

25
Q

Hgb on UA but no cells = ?

A

systemic hemolysis

ie. sickle cell

26
Q

Grade for Transitional cell CA with atypical cells slosely resembling normal?

A

grade I

27
Q

Grade fro Transitional cell CA with increased mitoses, nuclear pleomorphism, tumor giant cells:

A

Grade III

28
Q

Most important determinant for prognosis in CA?

A

Staging!

29
Q

Stage if limited to mucosa but flat:

A

TIS – POOR PROG

30
Q

Staging if muscle layer affected:

A

T2a/b

superficial vs deep

31
Q

Stage if invading perivesical fat:

A

T3

32
Q

Stage if invading adjacent structures?

A

T4

33
Q

What does N1-3 staging indicate?

A

nodal involvement

34
Q

M1 staging denotes?

A

distant metastases

POOR PROG

**not surgical candidate

Tx= chemo

35
Q

Stage if limited to mucosa and pappilary appearance:

A

Ta

36
Q

Stage if invading lamina propria:

A

T1

37
Q

Schistosoma haematobium infx, think:

A

Squamous cell CA

**not in USA

38
Q

Childhood associated CA with good prog?

A

Rhabdomyosarcoma

39
Q

Non-epithelial bladder CA in adults with poor prog?

A

Leiomyosarcoma

40
Q

Two classifications of Urethritis:

A

Gonococcal
-Neisseria gonorrhea

Nongonococcal

  • E. coli, other enterics
  • Chlamydia in sexual active young adults
41
Q

Benign urethral neoplasm at meatus

HPV related

A

Papilloma

42
Q

Benign urethral neoplasm in females

painfull

red mass

meatus

A

Caruncle

43
Q

Malignant urethral neoplasm in elderly women

A

Squamous cell CA