11/2 Renal Path Flashcards

1
Q

Capillary basement membrane thickening

diffuse increase in mesangial matrix

Hyaline masses at glom periphery (Kimmelstiel-Wilson)

A

Diabetic nephropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Initial presentation of diabetic nephropathy:

A

microalbuminuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Ischemic or toxic tubular injury:

A

Acute tubular necrosis

or

acute tubular injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Inflammatory reaction of tubules and interstitium:

A

tubulointerstitial nephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

In addition to inadequate blood flow, what causes ischemic patterns in ATN?

A

hemolysis

mismatched blood transfusions

skeletal muscle destruction (myoglobin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Patchy pattern of ATN?

A

ischemic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

contiguous pattern of ATN?

A

toxic type

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Calcium oxalate crystals in tubular lumens?

A

Ethylene glycol poisoning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

PMNs/Eos

Edema

= ________ tubulointerstitial nephritis

A

acute

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

fibrosis

tubular atrophy

= __________ tubulointerstitial nephritis

A

chronic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Neoplasm related to tubulointerstitial nephritis:

A

multiple myeloma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most common poles of kidney affected by acute pyelonephritis due to reflux?

A

upper and lower

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Two ways to cause pelvocalyceal damage:

A

chronic pyelonephritis

analgesic nephropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Irregularly scarred surface of kidney:

A

Chronic pyelonephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

thyroidization

colloid casts

A

chronic pyelonephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

lymphocytes ACUTELY?

A

Acute DRUG-induced interstitial nephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

classically seen with chemo?

A

Urate nephropathy

**precipitation of uric acid crystals in renal tubules

18
Q

Bence Jones proteins:

A

Multiple myeloma

19
Q

Hyaline deposition in arterioles d/t endothelial cell injury

A

nephrosclerosis

20
Q

“flea bitten” appearance of kidney

A

malignant nephrosclerosis

21
Q

“Onion skinning” of vessels

A

Malignant nephrosclerosis

22
Q

BP defining malignant nephrosclerosis:

A

Diastolic > 120

23
Q

Renal artery stenosis in young female, think:

A

fibromuscular dysplasia

24
Q

75% of classic HUS (hemolytic uremic syndrome) associated with?

A

E. coli (0157:H7)

25
Factor H deficiency?
Familial HUS
26
Fever neurologic sx MAHA thrombocytopenia renal failure
Idiopathic TTP
27
Most common type of kidney stone:
calcium oxalate calcium phosphate
28
Radiolucent stones
uric acid
29
stones from urea splitting bacteria?
Magnesium Ammonium Phosphate
30
Tumor associated with tuberous sclerosis
Angiomyolipoma **benign
31
Tumor Mahogany brown abundant mitochondria benign
Oncocytoma
32
Most common renal malignant tumor:
Renal cell carcinoma
33
Von hippel-Lindau syndrome chromosome 3p25.3
Renal cell carcinoma
34
Bright yellow tumor
renal cell carcinoma
35
renal cell carcinoma w/loss of 3p
clear cell
36
renal cell carcinoma foam cells trisomy 7, 17, loss of Y
Papillary
37
renal cell carcinoma vegetable like cells
chromophobe
38
RCC tends to invade/travel along:
renal vein
39
most common mets for RCC:
lung bone
40
identical to tumor for in bladder?
Urothelial (transitional cell) carcinoma of the renal pelvis