UPPER RESPIRATORY DRUGS (EXAM 3)

Question 1

ANTIHISTAMINES (1ST)

MED?
CROSSES?

Answer 1

DIPEHHYDRAMINE (BENADRYL)

BLOCKS HISTAMINE

CROSSES BLOOD BRAIN EASIER

PREGO-AVOID- DECREASE MILK

Question 2

ANTIHISTAMINES (2ND)

FEW?
MEDS?

Answer 2

FEW S/E
WORKS PERIPHERALLY

AZELASTINE (SPRAY)
CETRIZINE (ZYRTEC)
LORATADINE (CLARITIN)

Question 3

NASAL DECONGESTANTS

MED?
FREQUENT USE??

Answer 3

STIMULATE ALPHA ADRENERGIC
CONSTRICTION = DECREASE SECRETIONS
FEW S/E

OXYMETAZOLINE (AFRIN)
FREQUENT USE=REBOUND CONGESTION!!!!!

Question 4

SYSTEMIC DECONGESTANTS - ALPHA ADRENERGIC AGONISTS

SHORT OR LONG?
USE?
INCREASE?
MEDS?

Answer 4

RELIEVE CONGESTION LONG TIME!!!
ALLERGIC RHINITIS

INCREASE BP AND GLUCOSE!!!

PSEUDOEPHEDRINE (SUDAFED)
PHENYLEPHRINE HYDROCLORIDE

Question 5

INTRANASAL GLUCOCORTICOIDS

DECREASE?
COMBINE?
MEDS?

Answer 5

DECREASE RHINORRHEA, SNEEZE, CONGESTION
COMBINE W ANTIHISTAMINE

1-2 SPRAYS

SHORT TERM
DECREASE SYSTEMIC EFFECTS

BUDESONIDE
FLUTICASONE

Question 6

ANTITUSSIVES

SUPPRESS???

Answer 6

SUPPRESS COUGH

BENZONATATE (TESSALON)
CODEINE
DEXTROMETHORPHAN (BENYLIN)
HYDROCODONE

IN BREASTMILK

Question 7

EXPECTORANTS

MED?
LOOSENS?

Answer 7

GUALFENESIN (MUCINEX)

LOOSEN SECRETIONS
COUGH TO CLEAR