ANTIBACTERIALS (EXAM 3)

Question 1

PENICILLINS

S/E?
A/E?
INTERVENTIONS?

Answer 1

S/E: ALLERGY, D/N, VOMIT, PAIN @ INJECTION

A/E: BACTERIAL RESISTANCE, ALLERGIC, C.DIFF, RASH, PRURITUS, D/N, FEVER, DROWSY, ANAPHYLAXIS (ANGIOEDEMA, CIRCULATORY COLLAPSE, CARDIAC ARREST, NEPHROTOXICITY)

INTERVENTIONS: SUPERIN, C/S, ALLERGIC TO 1 AND 2 DOSE

Question 2

CEPHALOSPORINS

MED?
ALLERGIC TO?
S/E?
A/E?
GIANT?
DRUG INTERACTIONS?
INTERVENTIONS?

Answer 2

CEFTRIAZONE (ROCEPHIN)!!!!!! 3RD

ALLERGIC TO PCN

S/E: N/V/D, CLOTTING!!!!

A/E: NEPHROTOXICITY, STEVENS, ANAPHYLAXIS, THROMBOCYTOPENIA

GI
I NCREASE GLUCOSE
A NAPHYLAXIS
N EPHROTOXICITY
T HROMBOCYTOPENIA

DRUG INTERACTIONS: ALCOHOL

INTERVENTIONS: C/S, SUPER, WITH FOOD!!

Question 3

MACROLIDES

MED?
SUB?
S/E?
A/E?
INTERVE?
DRUG INTERAC?

Answer 3

AZITHROMYCIN!!!!

PCN SUB

S/E: N/V/D, CRAMP, PHOTOSENS!!, HA, FATIGUE,DIZZY, ORAL CANDIDIASIS!!

A/E: ANAPHY,SUPER,HEPATOTOXICITY, STEVEN, BLOOD DYSCRASIAS

INTERVENTIONS: C/S, LIVER DAMAGE, ANTACIDS 2 HRS BEFORE/AFTER!!!! (TAKEN AT SAME TIME DECREASES ABSORPTION), D

DRUG INTERACTIONS: INCREASE DIGOXIN, CYCLOSPORINE, WARFARIN. DECREASE PCN

Question 4

GLYCOPEPTIDES

MED?
WHAT IS CAUSED BY CDIFF?
S/E?
A/E?
FONT?
INTERVE?

Answer 4

VANCOMYCIN!!!!!

MRSA, PSEUDOMEMBRANOUS COLITIS CAUSED BY CDIFF

S/E: N/V, DIZZY, SUPER

A/E: OTOTOXICITY, NEPHRO,ANAPHY, BLOOD DYS, STEVEN, CDIFF - IV TOO FAST,HYPO,RED BLOTCH!!,TOXIC

FONT- FLUSHING, OTO, NEPHRO, THROMBOPHLENITIS

INTERVENTIONS: C/S, 1-2 HR IV,BP, RENAL TESTS (BUN AND CREATININE), HEARING

Question 5

TETRACYCLINES

MED?
S/E?
A/E?
DRUG FOOD INTERAC?
INTERVEN?

Answer 5

DOXYCYCLINE!!!!

S/E: N/V/D, PHOTOSE!!!, DISCOLORATION OR HYPOPOPLASIA OF TEETH!!!, STUNT GROWTH!!, NO KIDS UNDER 8, STOMATITIS, GLOSSITIS

A/E: ANAPHYLAXIS, CDIFF,OTO,HEPATO,NEPHRO,PANCYTOPENIA, STEVENS

DRUG FOOD INTERAC: MILK(DECREASE ABSO), ANTACIDS, BC!!!!!, PCN, AMINOGLYCOSIDES

INTERVEN: C/S, KIDNEY AND LIVER, EMPTY STOMACH AND WATER!!!!!, SUNSCREEN, AVOID MILK, IRON, ANTACIDS!!! NONHORMONE BC (D)!!!

Question 6

AMINOGLYCOSIDES

MED?
S/E?
A/E?
INTERVE?

Answer 6

GENTAMYCIN!!!!

S/E: PHOTOSEN, SUPER, STOMATITIS, N/V, FEVER,LETHARGY

A/E: ANAPHY,SEIZURES,OTO(HEAR),NEPHRO(KID), CDIFF, STEVEN

MORE TOXIC

INTERVENTIONS: C/S, HEARING LOSS AND RENAL, P AND T DRUG LEVELS, OTO-VERTIGO AND TINNITUS

Question 7

SULFONAMIDE

MED?
WHAT?
S/E AND A/E?
INTERVE?

Answer 7

TRIMETHOPRIM-SULFAMETHOXAZOLE (BACTRIM)

URINARY TRACT ANTIINFECTIVE
SYNERGISTIC

S/E AND A/E: GI, STOMATITIS, PHOTOSEN,CRYSTALLURIA, RENAL FAIL,BLOOD DYS, STEVENS

INTERVENTIONS: INCREASE FLUID 200, CBC AND RENAL, RASH, SUPER, AVOID 3RD TRIMESTER!!!, AVOID ANTACIDS!!, SORE THROAT, BRUISING, BLEEDING!!! NO SUN

Question 8

FLUROQUINOLONES

MED?
TREATS?
S/E?
A/E?
DRUG INTERAC?
INTERVEN?

Answer 8

CIPROFLOXACIN

TREAT UTI

S/E: RASH, N, HA, PAIN,V,DIZZY, CHANGE IN TASTE!!, DECREASE SLEEP!!, PHOTOSEN

A/E: HEART DYSRHYTH!!!, NEUROTOX,STEVENS, BLOOD GLUCOSE, TENDON RUPTURE!!!!!, PERIPHERAL NEUROPATHY!!!

DRUG INTERAC: ANTACIDS AND MILK DECREASE ABSOR, INCREASE EFFECT OF ORAL HYPOGLYCEMICS

INTERVENTIONS: C/S, HEART RATE AND RHYTHM, IV 60-90, INCREASE FLUID 2000, NO CAFFEINE, STOP DRUG IF THERE IS TENDON/JOINT PAIN!!!!!!!!