GI MEDS (EXAM 3)

Question 1

DOPAMINE ANTAGONISTS

MED?
INHIBITS?
USES?
S/E?
A/E?

Answer 1

PROMETHAZINE (PHENERGAN)

BLOCKS DOPAMINE
INHIBITS V

USES: N/V, CHEMO, RADIATION

S/E: DRY MOUTH, SEDATION, C, ORTHO HYPO, TACHY

A/E: EPS WITH INCREASED THERAPY (PARKINSONS)

Question 2

SEROTONIN ANTAGONISTS

INCREASE EFFECT W?
USES?
S/E?

Answer 2

ONDANSETRON (ZOFRAN)

BLOCK VAGAL NERVE
INCREASE EFFECT WITH DEXAMETHASONE

USES: POSTOP, CHEMO

S/E: HA, DIZZY, HYPO,PALPITATIONS, CONSTIPATION,EDEMA, FATIGUE

Question 3

METOCLOPRAMIDE (REGLAN)

BLOCKS?
INCREASE DOSE?
S/E?

Answer 3

BLOCKS DOPAMINE

POSTOP EMESIS, CHEMO, RADIATION

INCREASE DOSE: SEDATION, FATIGUE

S/E: DROWSY, FATIGUE, HA, C, URINARY RETENTION, BLUR, TACHY, EPS

Question 4

OSMOTIC (SALINE) LAXATIVES

MED?
PULLS WHAT?
S/E?

Answer 4

MAG SALTS-MAG HYDROXIDE (MILK OF MAGNESIA)
MAG CITRATE

PULL WATER INTO COLON
WATERY STOOL

BOWEL PREP FOR SURGERY

S/E: FLUID AND ELECTROLYTE IMBALANCE, CRAMPS, N/V, FARTS, D

Question 5

OSMOTIC LAXATIVE

MED?
DECREASE WHAT??
S/E??

Answer 5

LACTULOSE

MANAGE HEPATIC ENCEPHALOPATHY
DECREASE BLOOD AMMONIA!! IMPROVE MENTAL

S/E: FART, D, CRAMPS, V/N

Question 6

STIMULANT LAXATIVES

MED?
TREATS?
S/E?
A/E?

Answer 6

BISACODYL (DULCOLAX)

OPIOID CONSTIPATION
TREAT CONSTIPATION

S/E: DIZZY, CRAMP, N/D, K AND CA IMBALANCE, RED AND BROWN URINE!!!!!

A/E: OVER USE LEADS TO DECREASED TONE AND SENSATION

Question 7

BULK FORMING LAXATIVES

MED?
ABSORB?
A/E?

Answer 7

PSYLLIUM (METAMUCIL)

ABSORB WATER INTO INTESTINE
SHORT TERM, IBS, ILEOSTOMY, COLOSTOMY

A/E: DECREASE FLUID = OBSTRUCTION

MIX WITH WATER, STIR, FOLLOW W WATER

Question 8

EMOLLIENTS (LUBRICANTS AND STOOL SOFT)

MED?
PREVENT?

Answer 8

DOCUSATE SODIUM (COLACE)

INCREASE WATER ACCUMLATION
PREVENT CONSTIPATION AND DECREASE STRAINING