DIABETES (EXAM 3)

Question 1

TYPE 2
SECOND GENERATION SULFONYLUREAS

Answer 1

GLIPIZIDE (GLUCOTROL)

INCREASE INSULIN
CONTROL HYPERGLY

HYPOGLY - ALCOHOL

SLOW 1-2 DAILY
OK BREATFEED

Question 2

MEGLITINIDES

Answer 2

NATEGLINIDE (STARLIX) AND REPAGLINIDE (PRANDIN)

INCREASE INSULIN
CONTRAINDICATED: LIVER DISEASE

CAUSE HYPOGLY

SHORTER BURSTS!!!! 15-30 MIN BEFORE MEAL

> 10 YRS

Question 3

BIGUANIDES

Answer 3

METFORMIN (GLUCOPHAGE)

DECREASE GLUCOSE
INCREASE INSULIN SENSITIVITY

DOESNT CAUSE HYPOGLY
>10 YRS
OK BREAST

IODINATED CONTRAST MEDIA INCREASE RISK OF RENAL FAIL AND LACTIC ACIDOSIS (HOLD 48 HRS) !!!!

Question 4

ALPHAGLUCOSIDASE INHIBITORS

Answer 4

ACARBOSE (PRECOSE)

BLOCK ENZYME FOR RELEASE OF GLUCOSE FROM COMPLEX CARBS

DECREASE DIGEST OF GLUCOSE
MONOSACCHARIDE TO BE ABSORBED!!

GIVE AT START OF MEAL