Update in Clinical Cardiology - Harvard Flashcards

1
Q

5 tx anti-ischémiques/

A

1) nitrates:
pour sx, pas d’effet sur mortalité
2) BB
PO seulement SI pas à risque de choc/HF
3) BCC
Si ischémique malgré BB
4) Morphine
Dlr, CHF, agitation
5)O2
Si hypoxemique

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2
Q

Délai d’intervention SCA

A
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3
Q

Étude SENIOR-RITA 2024

A

Invasive vs conservative in 1518 pts NSTEMI ≥ 75 ans
1) Aucune différence de mortalité CV
2) Réduction 25% taux d’IM
3) Complication procédurale < 1%

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4
Q

Étude TIMI-38 2007

A

13k SCA
1) Mortalité/IM/AVC
Prasugrel < Clopidogrel

2) Saignement
Prasugrel > Clopidogrel

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5
Q

Étude PLATO 2009

A

18k SCA
1) Mortalité/IM/AVC
Ticagrelor < Clopidogrel

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6
Q

Étude ISAR-REACT 5 2019

A

4k SCA
1) Mortalité/IM/AVC
Prasugrel < Ticagrelor

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7
Q

Choix d’anticoagulothérapie en SCA

A

STEMI:
1) Primary PCI -> Héparine non fractionnée
2) Lytics-> Enoxaparine

NSTEMI:
1) Invasive -> Héparine non fractionnée
2) Conservative -> Enoxaparine

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8
Q

Cible LDL-C post-SCA en prévention secondaire

A

Statine et Ezetimib et/ou PCSK9i pour LDL < 1.4 mmol/L
-> (viser <1 mmol/L si possible)

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9
Q

Take home points SCA

A
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10
Q

Tx ANOCA/INOCA

A
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11
Q

NPO ou pas avant intervention?

A

Pas de différence entre NPO 3h vs 13h

-> Étude SCOFF

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12
Q

sx le plus commun d’occlusion coronaire totale

A

Dyspnée à l’effort

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13
Q
A
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