Unit II: Limb Development Flashcards

1
Q

Which appears first: the upper limb or the lower limb?

A

Upper

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2
Q

The limb bud consists of:

A
  1. AER

2. central core of mesenchyme

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3
Q

The most critical period of limb development is ___ after fertilization

A

24-36

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4
Q

What is syndactyly?

A

The fusion of digits

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5
Q

What is cutaneous syndactyly?

A

Failure of webs to degenerate

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6
Q

What is osseous syndactyly?

A

Fusion of bones

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7
Q

What is polydactyly?

A

Extra digits

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8
Q

Which bone is homologous to the humerus?

A

Femur

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9
Q

Which bone is homologous to the tibia?

A

Radius

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10
Q

Which bone is homologous to the ulna?

A

Fibula

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11
Q

Which bone is homologous to the metatarsals?

A

Metacarpals

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12
Q

The thumb is homologous to the ___

A

Great toe

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13
Q

The upper limb rotates ___ degrees ___

A

90, laterally

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14
Q

The lower limb rotates ___ degrees ___

A

90, medially

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15
Q

What is amelia?

A

Complete absence of a limb

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16
Q

What is mecromelia?

A

Partial absence of a limb

17
Q

Amelia and mecromelia are involved with the drug ___

A

Thalidomide

18
Q

What is talipes equinovarus?

A
  1. club foot
  2. 1/1000 births
  3. medially and inverted
  4. oligohydramnios
19
Q

What is congenital hip dysplasia?

A
  1. the joint capsule is lax at birth with a shallow acetabulum and small femoral head
  2. more common in females