Unit 8 Male Reproductive Function

Question 1

What is the role of Sertoli cells?
a) Produce testosterone
b) Regulate the LH surge
c) Support spermatogenesis and form the blood-testis barrier
d) Convert testosterone to DHT

Answer 1

c) Support spermatogenesis and form the blood-testis barrier

Explanation: Sertoli cells nourish developing sperm, secrete inhibin, and create a protected environment for spermatogenesis.

Question 2

What hormone is essential for spermatogenesis support within seminiferous tubules?
a) FSH
b) LH
c) Progesterone
d) DHT

Answer 2

a) FSH

Explanation: FSH targets Sertoli cells, promoting spermatogenesis and production of androgen-binding protein.

Question 3

What is the role of androgen-binding protein (ABP)?
a) Transports testosterone in blood
b) Binds testosterone in seminiferous tubules to concentrate it
c) Inhibits FSH
d) Stimulates spermatid maturation

Answer 3

b) Binds testosterone in seminiferous tubules to concentrate it

Explanation: ABP keeps local testosterone levels high to support sperm development.

Question 4

What is dihydrotestosterone (DHT) and where is it important?
a) A weak androgen; needed in the hypothalamus
b) A testosterone precursor
c) A hormone made in ovaries
d) A potent androgen; critical for male external genitalia development

Answer 4

d) A potent androgen; critical for male external genitalia development

Explanation: DHT is formed from testosterone by 5α-reductase and drives development of prostate, penis, and scrotum.

Question 5

Which cells in the testes produce testosterone?
a) Sertoli cells
b) Granulosa cells
c) Leydig cells
d) Thecal cells

Answer 5

c) Leydig cells

Explanation: Leydig cells, located in the interstitial space of the testes, respond to LH and produce testosterone.