Unit 8 - Genetics Flashcards
nondisjunction
when chromosomes don’t separate properly during meiosis, too many or too few in each cell
trisomy
having an extra chromosome in zygote cell (3 instead of 2)
organisms with extra chromosomes usually ____, organisms missing chromosomes usually _____
survive, die
polyploidy
too many chromosomes
what does polyploidy cause in animal cells
death
what does polyploidy cause in plants
doesn’t do anything, common in plants
deletion
large section removed
duplication
section is duplicated
inversion
sections flip order
reciprocal translocation
part of one chromosome exchanged with another
ABCD – ACD
deletion
ABCD – ABCBCD
duplication
ABCD – ACBD
inversion
ABCD – MNOD
MNOP–ABCP
reciprocal translocation
genetics
study of how traits are passed from one gen to the next, specifically how genes affect that
heredity
passing of characteristics from parent to offspring
gene
section of DNA found on chromosome
traits
characteristic of an individual
Gregor mendel
Austrian monk that studied pea plants to determine how traits are passed, “father of modern genetics”
principle of dominance
dominant and recessive traits
segregation
traits for tallness and shortness seperated during formation of gametes
homo dominant:hetero:homo recessive
genotypic ratio
dominant:recessive
phenotypic ratio
shows two types of gametes from each parent in punnet square w/ 4 boxes, one trait
monohybrid cross
punnet square that shows two traits in 16 boxes
dihybrid cross
mendelian inheritance
dominant or reessive, homo and hetero
one allele not completely dominant over another, phenotype is between homo phenotypes
incomplete dominance
red and white flower crossed, pink result
incomplete dominance
heterozygote shows phenotypes of both alleles
codominance
white and black chicken crossed, offspring has black and white feathers
codominance
gene with more than two alleles
multiple alleles
eye color, each person has two alleles in a diploid cell for eye color, many eye color alleles in the human population
multiple alleles
blood genotype AA or AO, phenotype?
A
blood genotype BB or BO, phenotype?
B
blood genotype AB, phenotype?
AB
blood genotype OO, phenotype?
O
traits controlled by two or more genes
polygenic traits
skin color controlled by more than four genes
polygenic trait
ability of a gene to affect an organism in multiple ways (many phenotypes)
pleitropy
sickle-cell disease, causes many symptoms
pleitropy
gene at one location alters expression of a gene in another location
epistasis
BB/Bb/bb determines coat color but CC/Cc/cc determines pigment
epistasis
chromosome pairs 1-22
autosomes
chromosomes that determine sex
sex chromosomes, pair 23
XX (male or female)
female
XY (male or female)
male
gene is only found on X chromosome
sex-linked traits
male pattern baldness, colorblindness, hemophilia
sex-linked traits
someone who carries a sex-linked trait but is not affected by it
carrier, usually women
women can only have a sex-linked disease if…
father has it and mother is carrier or has it
what is trisomy 21?
down syndrome
most genetic disorders are in (recessive/dominant) alleles
recessive
condition that causes formation of thick mucus in lungs and digestive tract
cystic fibrosis
about how many white Americans carry cystic fibrosis
1 in 20
condition that causes fat to accumulate in central nervous system
tay-sachs disease
who normally has tay-sachs disease
Jews from eastern europe
is cystic fibrosis caused by recessive or dominant alleles
recessive
is tay-sachs disease caused by recessive or dominant alleles
recessive
is tay-sachs disease lethal
yes
condition where the body can’t digest the amino acid phenylalanine to amino acid tyrosine
phenylketonuria (PKU)
what does phenylketonuria cause
damage to the central nervous system, sometimes retardation in infants if not found
condition that causes breakdown of parts of the brain
huntington’s disease
when does onset huntington’s disease happen
30-50 yrs of age
diagram of how traits are inherited
pedigree
heterozygous person who “carries” a recessive trait and may pass it onto their children but it doesn’t affect them
carrier