Unit 5 review Flashcards
Botulin
Neurotoxin that blocks neuromuscular conduction
CP and torticollis
IM
dry mouth
Baclofen
Muscle relaxer for spastic CP
mechansim unknown
oral or intrathecally
central acting skeletal muscle relaxer for CP
Corticosteroids
antiinflammatory and autoimmune
duchesne MD
Myasthenia gravis
Must taper it down
Benzodiazepines
adjunct relief for skeletal muscle spasms for CP
1st line treatment for hyperthyroidism
methimazole (MTZ, Tapazole) or PTU propythlthiouracil
Adjuct therapy with inderal, a B-adrenergic blocker if marked symptoms
Cholinergic crisis
occurs from over meds of anticholinergic meds for myasthenia gravis
Severe muscle weakness (possible affecting respiratory), sweat, increase salivation, bradycardia, hypotension.
Wear medical alert bracelet
Autoimmune neuromuscular disorders
Dermatomyositis: muscles and tissues; often from virus or meds, genetics, more in girls 5-14
Guillain-Barre: peripheral nervous system is attacked, but doesn’t affect brain or spinal cord. Inflammation and demyelinization of nerves. Triggered from flu like respiratory infection or acute gastroenteritis with fever. Paralysis, resp involvement, numbness and tingling, severe muscle weakness, quick onset, bottom to top, 2-4 week course. Plasma exchange, IVIG, corticosteroids
Myasthenia gravis: genetic, thru birth, in childhood. No cure. Progressive weakness and fatigue of skeletal muscle. Crisis is a medical emergency Sudden resp distress, dysphagia, dysarthria, ptosis, dipllopia, tachycardia, anxiety, rapid increasing muscle weakness. Too much anticholinergics may cause it. Prevent resp problems, promote nutrition, wear bracelet
3 types SMA spinal muscular atrophy
1: Werdnig-Hoffman: birth - 6 months, general weakness, can’t sit, weak cry, poor suck, weak swallow and breathing. Progress to early death. Ventilators, enteral feeding
2. Intermediate: 6-18 months, proximal muscles more affected, resp muscles, scoliosis, slower progress, survive to adult with respiratory status being maintained
3: Kugelberg-Welander disease-juvenile SMA, after 18 months, taken at least 5 steps, weakness in shoulder, hip, thigh, upper back, resp may be involved, scoliosis, slow progression, walking usually maintained until adolescence.
Slipped capital femoral epiphysis
SCFE femoral head dislocates from the neck and shaft of femur at epiphyseal plate. males 11-16, African, obese
Acute: cant bear weight, pain sudden
Chronic: pain and limp
decreased ROM, external rotation of hip, DO NOT perform passive motion
Childhood FX
Plastic or bowing deformity, bone not broke
Buckle fx: compression,
Greenstick, incomplete, most common in childhood (wrist and forearm)
Complete: broke in two
Spiral: most common abuse fx (femur, humerus, rib)
Osteomyelitis
infection bone and tissue
staph aureus
bacteria from blood invades bone or joints
aspiration and culture (4-6 wks of abx)
pain, swelling, warm joints, decreased ROM, possible fever
Septic Arthritis
bacteria invade the joints, usually hip and knee.
From blood, puncture, injection, venipuncture, wound, surgery, injury, staph aureus
Medical emergency: joint cartilage deteriorates, AVN,
Sudden onset of fever, moderate to severe pain
Predisposing factors: resp infection, otitis media, skin or tissue infection, traumatic puncture wounds, femoral venipuncture,
hypoglycemia
Poor feed, jittery, lethargy, high pitched weak cry, apnea, cyanosis, seizures, may by asymptomatic,
Newborn: rosy cheeks, ruddy skin, short neck, buffalo hump, massive shoulders, distended abdomen, Increased subQ fat, listless, hypotonia, apathy, poor feed, apnea, low O2, cyanosis, temp instable, pallor, sweat, tremors, irritable, seizures
Med for Diabetes Insipidus
DDAVP, vasopressin
Intranasal, PO, SubQ q8-12 hrs, dose depends on urine specific gravity 1.010, age and output, keep in fridge, clear nostrils, repeat if sneeze, overdose: confusion, headache, drowsy, rapid wt gain.
Maintain and monitor fluids, daily wt, monitor for dehydration, monitor BP close, notify doc if urine > 1000ml per hour twice in row, if fluids are stopped, could lead to hypernatremia and seizures
Precocious puberty
before age 9 for boys
before age 6 for african girls
before age 7 for white girls
If med is stopped, puberty will occur again
Treat child like age, not what they look like.
Slow it with Depo-provera injections, Cycrin tablets
Central puberty: most common, release of GnRH prematurly > release of LH and FSH > gonads release sex hormones.
Peripheral puberty is just early overproduction of sex hormones
Hyperthyroidism
Nervous-anxiety diarrhea heat intolerance wt loss smooth velvety skin increased rate of growth
Hypothyroidism
Tired constipation cold intolerance wt gain dry thick skin, edema of face decreased growth
Rapid acting insulin
15; 30-90; 3-5 hrs
Aspart-novolog
Lispro-humalog
Glulsine-apidra
Short acting insulin
30-60; 2-4; 5-8
Regular-Humilin R, Novolin R