Unit 5: Immunity Flashcards
active immunity
defenses that arise when a pathogen infects the body and prompts a primary or secondary immune response
passive immunity
passed from mother to fetus
- IgG in blood provide guard against pathogens that have never infected newborn
- IgA transferred in breast milk, provide immunity to digestive tract and protect mucous membranes
immunization
- active
- antigens introduces into body, inducing primary immune response and immunological memory
artificial passive immunization
antibodies from an immune animal are injected into a non-immune animal
Allergies
- exaggerated response
1. IgE antibodies (produced after initial exposure) bind to receptors on mast cells
2. On second exposure, IgE molecules bind to allergen
3. Cross linking of IgEs triggers release of histamine and other chemicals leading to allergy symptoms
anaphylactic shock
after allergen exposure, widespread release of mast cell contents trigger dilation of peripheral blood vessels
-causes blood pleasure to drop and constriction of bronchides
Antigenic Variation
- changes in epitope expression
- an alteration in how a pathogen appears to immune system can allow pathogen to avoid a secondary response
Latency
-virus may enter a largely inactive state
HIV
- infects helper T cells, loss makes body more prone to serious infection
- mutates at a very high rate
- product DNA is integrated into host cells, can remain latent and go undetected