Unit 4 - Other CNVM

Question 1

What other causes of CNVM are there?

Answer 1

1. Myopia
2. Doyne Honeycombe retinal dystrophy (Dominant drusen)
3. Trauma
4. Choroidal naevus
5. Mactel 2
6. Angiod streaks
7. Inflammatory causes

Question 2

Which study compared Lucentis to PDT in pathological myopia?

Answer 2

Radiance

Question 3

What fundal changes can you expect in pathological myopia?

Answer 3

Staphyloma
Mottled RPE
Tilted disc
Lacquer cracks
Tigroid/tessellated fundus

Question 4

What is the prevalence of pathological myopia?

Answer 4

1-3 of population, higher in East Asia

Question 5

In what proportion of pathological myopia would you expect CNVM?

Answer 5

approx 5-11%

Question 6

In what proportion of patients would you expect bilateral myopic CNVM?

Answer 6

15%

Question 7

What treatments are there for myopic CNVM?

Answer 7

1. PDT
2. Laser
3. Anti-VEGF
4. Surgical - macula translocation

Question 8

The REPAIR trial looked at what?

Answer 8

Lucentis in myopic CNVM
21% only needed 1 injection

Question 9

Which study looked at eylea versus sham for myopic cnvm??

Answer 9

Myrror
Statistically superior to sham +12 lettrs versus -2