Case records Flashcards
1
Q
What are the differences between aflibercept and faricimab?
A
Eylea is a VEGF trap, Vabymso is an VEGF A antibody and Ang 2 action
2
Q
What is VEFG-A thought to regulate?
A
Endothelial proliferation
Vascular permeability
Neovascularisaton
3
Q
What does the anti ANG-2effect?
A
- improves vascular stability
- desensitizes vessels to actions of VEGF-A
4
Q
What is eylea?
A
115kDA fusion protein. Binds to VEGF A, VEGF B and PIGF
5
Q
What types of endophthalmitis would you expect after an IVI?
A
- Sterile
- Infective
6
Q
What modes of action are thought to trigger endopthalmitis?
A
- Silicon inside syring
- Immunological reaction to drug itself
- Infection caused by injection
7
Q
A