Case records Flashcards

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1
Q

What are the differences between aflibercept and faricimab?

A

Eylea is a VEGF trap, Vabymso is an VEGF A antibody and Ang 2 action

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2
Q

What is VEFG-A thought to regulate?

A

Endothelial proliferation
Vascular permeability
Neovascularisaton

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3
Q

What does the anti ANG-2effect?

A
    1. improves vascular stability
    1. desensitizes vessels to actions of VEGF-A
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4
Q

What is eylea?

A

115kDA fusion protein. Binds to VEGF A, VEGF B and PIGF

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5
Q

What types of endophthalmitis would you expect after an IVI?

A
  1. Sterile
  2. Infective
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6
Q

What modes of action are thought to trigger endopthalmitis?

A
  1. Silicon inside syring
  2. Immunological reaction to drug itself
  3. Infection caused by injection
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7
Q
A
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