unit 4 immunology: vaccination Flashcards
vaccinations
Purpose is to induce a specific primary immune response without actually getting the disease
When the actual disease is encountered, a secondary response will be launched
types of vaccines
influenza and hepatitis A: injected with dead organism, inactivated, or killed vaccine
measles, mumps, rubella: Genetically altered by weakening it and allowing a immune response. getting a vaccine and feeling ill but it still. Generates the antibodies and trigger you pathways
tetanus: toxoid vaccine, injecting the proteins from tetanus and change the proteins your body still thinks is the real thing
hepatitis B, HPV: subunit vaccine, injected with a fragment of the pathogen required to stimulate the immune system
mRNA: uses host cell machinery to make protein antigens, nucleic acid vaccine
HIV and AIDS
Human immunodeficiency virus (HIV) can eventually lead to Acquired Immune Deficiency Syndrome (AIDS)
- HIV destroys helper T cells
- Without helper T cells, B cells and cytotoxic T cells cannot function
- Without functional B cells and cytotoxic T cells, immune system starts to fail
- Progressive weakened immune system leads to AIDS
- Without a strong immune system, become susceptible to infections, allowing life-threatening opportunistic infections and cancers to thrive