Unit 1 endocrine system (hormones) Flashcards

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1
Q

Adrenocorticotropic hormone function after released

A

protects the body in stress situations (pains and injuries)

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2
Q

Growth hormone

A

leads to physical growth
increases metabolism, cell size, bone and muscle growth, promotes healing and tissue repair

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3
Q

Thyroxine hormone function

A

increases metabolic rate, increased breakdown of fats and carbohydrates, affects protein metabolism, synthesis of sodium potassium pumps, and is involved in the development of nervous and skeletal system

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4
Q

calcitonin hormone function (thyroid)

A

regulated by negative feedback of calcium ion levels in the blood

reduces blood calcium and phosphate levels

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5
Q

parathyroid hormone

A

raises calcium blood levels
regulated by negative feedback of calcium ion levels

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6
Q

Adrenal cortex: outer zone: aldosterone

A

Outer zone produces mineralocorticoids (steroids of salt and water balance)

Aldosterone: reabsorption of Na+, leading to increased water reabsorption and execration K+, H+ from the kidney

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7
Q

Adrenal cortex middle zone: cortisol

A

Middle zone: produces glucocorticoids (steroid hormone produced from the adrenal glands)

Cortisol: stimulated by the anterior pituitary, responds to stress, increases muscle metabolism, increases sugar storage via gluconeogenesis, other effects

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8
Q

Adrenal cortex inner zone: androgens

A

Inner zone: produces androgens

In male and female is the primary source until puberty when sex glands take over involved in the development of secondary sex characteristics

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9
Q

Adrenal Medulla: Epinephrine (adrenaline) and Norepinephrine (noradrenaline)

A

Both are neurotransmitters that respond to fear, excitement, and danger

Both hormones increase blood pressure

Epinephrine increases blood flow to the heart and muscles

Norepinephrine decreases blood flow to the intestines and the skin

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10
Q

Pancreas: glucagon glucose is high

A

Produced by beta cells

Lowers blood glucose levels

hypoglycemia

Increasing cellular glucose uptake through cells

causes low blood sugar levels

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11
Q

Pancreas: insulin glucose is low

A

Produced by beta cells

hyperglycemia

Increases blood glucose levels

stimulates glucagon to the liver to make glucose

high blood sugar levels

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12
Q

loss of blood glucose level control

A

Diabetes mellitus
* Loss of insulin
* No uptake of glucose (leading to hyperglycemia)
* Leads to ketoacidosis

“exhausted”
* Hyperinsulinemia
Leads to hypoglycemia
Symptoms: anxiety, sweating, tremors, increased heart rate
Leads to unconsciousness, coma

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13
Q

Thymosins- Thymus glands

A

Secretes thymosin (hormone)- involved in the development of the immune system

Larger as a baby and decreases in size as age ^

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14
Q

Pineal gland

A

Secretes melatonin – acts on the hypothalamus to change levels of luteinizing hormone

Also responds to light and may be related to daily rhythms

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15
Q

Homeostasis

A

Homeostasis is the process by which the body maintains a stable internal environment, such as temperature, pH, and fluid balance, despite changes in external conditions. It ensures that the body’s systems function properly.

Stress = any stimulus that leads to an imbalance to
homeostasis
* External: eg. heat, cold, loud noise
* Internal: eg. pain, emotion, increased blood pressure

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16
Q

adaptation

A

Body must adapt and regain homeostasis through negative feedback; goes back to normal

17
Q

endocrine vs nervous system

A

Nervous system: releases neurotransmitters, which acts locally (nerve, muscle, glands), slow acting, and long lasting

Endocrine system: releases hormones, which act at distant location around body, slow acting, long lasting

18
Q

Dealing with stress (phases)

A

Alarm phase
Sympathetic Nervous system stimulated fast
Fast acting but short lived

Resistance
Endocrine system kicks in
Long lasting but needs time to get started

Exhaustion phase
Endocrine system breaks down
Hormone no longer works
Organ failure (irritable bowel syndrome, tumors, hypertension, depression)

19
Q

blood calcium levels

A

Calcium is mostly stored in the bone

Needs some circulating calcium for:
Blood clotting
Release of neurotransmitters
muscle contraction
Normal heartbeat
Normal function, need a constant blood calcium level

20
Q

control of blood calcium levels: calcitonin produced by thyroid gland

A

Released from thyroid gland when
blood calcium levels increase
Works to decrease blood calcium levels
to physiological conditions by:
-Stimulating osteoblasts to absorb calcium to make bone
-Reducing osteoclast activity

21
Q

Control of blood calcium levels: parathyroid

A

Released from parathyroid gland when
blood calcium levels decrease
* Works to increase blood calcium levels to physiological conditions by:
-Inhibiting osteoblasts
-Stimulating osteoclasts to
breakdown bone release calcium and phosphorus (phosphorus is excreted from the kidneys)
- Increasing calcium absorption in
the GI tract

22
Q

loss of blood calcium levels
hyperparathyroidism and hypoparathyroidism

A

Hyperparathyroidism
-Too much parathyroid hormone
-Over breakdown of bone
-Bone becomes weak

Hypoparathyroidism
-To little parathyroid hormone
-Insufficient extracellular calcium
-depolarization in the absence of stimuli
-Leads to tetany (twitches, spasms, convulsions)