Unit 1 endocrine system Flashcards
Gland
Organ that releases a secretion (hormone, enzyme, etc.)
Exocrine glands
Secretion is discharged onto the surface of an epithelium (e.g. skin, digestive tract, sudoriferous glands (sweat), mammary glands, salivary glands, pancreas (acinar cells)
Endocrine glands
Secretion (hormone) is discharged into
the interstitial fluid and enters the
bloodstream
ex. Pituitary gland, Thyroid, Adrenal glands, Pancreas (Islets of Langerhans)
Hormones
A molecule (chemical messenger) that is released in one part of the body and regulates the activity if another part of the body
functions of hormones
- Stimulate secretions by exocrine gland,
- secretion of hormones from other endocrine glands
- Regulate metabolic reactions and changes in body’s biochemistry
- Regulates muscle contraction and nervous stimulation
- Regulate growth and development
- Regulate reproduction
8 hormones from the hypothalamus
-Five “releasing” hormones
stimulates the anterior pituitary
-One “inhibitory” hormone
inhibits release of a hormone from the anterior pituitary
-Two are produced in the hypothalamus
-secreted by the posterior pituitary
hypothalamus and pituitary gland
Control center that targets the pituitary gland and homeostasis (blood osmotic pressure, glucose level, some hormone concentrations, temperature)
your hypothalamus communicates with the anterior pituitary lobe via hormones and the posterior lobe through nerve impulses.
Where things can go wrong
Over or under activity of endocrine glands can lead to
increased or decreased amounts, respectively, of hormone
secreted
hyposecretion vs hypersecretion
Hypersecretion is when an excess of one or more hormones is secreted from a gland.
Hyposecretion is when the number of hormones that are released is too low.
Thing go wrong for growth hormones - childhood
(anterior pituitary )
childhood
Pituitary dwarfism
-hyposecretion of epiphyseal plates close before normal
growth completes
-can be prevented by
administering growth
hormone before the
plates close
gigantism- abnormally large person caused by hypersecretion of calcium
Things go wrong growth hormone- adults
Simmond’s disease
-hyposecretion causes weakness, weight loss, body tissue wasting away
Acromegaly
- hypersecretion causes thickening of bones and various other tissues
things go wrong Thyroid through changed levels of thyroxin- childhood
Cretinism
-poor growth, lethargy,
easy weight gain,
mental delay (hyposecretion)
Things go wrong- Antidiuretic hormone (ADH)
hyposecretion of ADH leads to diabetes insipidus,
can be caused by damage of the posterior pituitary or the hypothalamus
symptoms (extreme thirst and polyuria)
Things go wrong- thyroid through changed levels of thyroxin- adult
Graves’ disease:
too much thyroxine, increased metabolic rate, nervous system, irritable, protruding eyes (hypersecretion, both adult and children)
myxedema:
decreased body metabolism, body tissue swelling, easy weight gain (hyposecretion, adult)
Goiter:
increase increased thyroid gland size lack of iodine in diet (hypersecretion)
Things go wrong-cortisol
Cushing syndrome: redistributed of body fat (buffalo hump) face swells, become thin, Flushed facial skin, Bruising and poor wound healing, Hyperglycemia (high blood glucose) , hypertension
Addisons disease Hypoglycemia (low blood glucose), Muscle weakness Mental lethargy, Weight loss