UNIT 3 - Muscular System Flashcards

1
Q

What are the types of muscle tissue?

A

The types of muscle tissue are skeletal, cardiac, and smooth muscle. Skeletal muscle is striated and voluntary, cardiac muscle is striated and involuntary, while smooth muscle is non-striated and involuntary.

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2
Q

What are the properties of muscle tissue?

A

The properties of muscle tissue include contractility, excitability, extensibility, elasticity, and conductivity. Each property plays a crucial role in muscle function.

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3
Q

What are the basic components of muscle cells?

A

The basic components of muscle cells include the sarcolemma, sarcoplasm, sarcoplasmic reticulum, and myofibrils.

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4
Q

What is the structure of skeletal muscle fibers?

A

Skeletal muscle fibers are arranged in myofibrils, which are further organized into sarcomeres, T-tubules, and terminal cisternae.

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5
Q

What is the myofilament structure?

A

The myofilament structure consists of actin (thin filaments), myosin (thick filaments), troponin, tropomyosin, and titin. These proteins are essential for muscle contraction.

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6
Q

What is the organization of a sarcomere?

A

A sarcomere contains the A band, I band, H zone, Z disc, and M line. Their appearance changes during contraction.

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7
Q

What is the sliding filament mechanism?

A

The sliding filament mechanism describes how actin and myosin interact to cause muscle shortening.

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8
Q

What are electrically excitable cells?

A

Electrically excitable cells have a resting membrane potential and utilize ion channels (leak, gated, and voltage-gated) for depolarization and repolarization.

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9
Q

What occurs at the neuromuscular junction (NMJ)?

A

At the NMJ, components such as the axon terminal, synaptic cleft, and motor end plate facilitate the initiation of muscle contraction.

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10
Q

What is excitation-contraction coupling?

A

Excitation-contraction coupling is the sequence of events that links the action potential to the sliding of myofilaments.

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11
Q

What is the muscle contraction cycle?

A

The muscle contraction cycle involves ATP hydrolysis, crossbridge formation, power stroke, and detachment.

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12
Q

How does muscle relaxation occur?

A

Muscle relaxation occurs as the muscle returns to its resting state, with the role of Acetylcholinesterase being crucial.

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13
Q

What are the energy sources for muscle contraction?

A

The energy sources for muscle contraction include immediate, glycolytic, and oxidative sources, utilizing ATP, creatine phosphate, glycolysis, and oxidative metabolism.

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14
Q

What are muscle twitch and tetanus?

A

Muscle twitch includes the latent period, contraction period, and relaxation period, while tetanus can be unfused (incomplete) or fused (complete).

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15
Q

What is the length-tension relationship?

A

The length-tension relationship describes how the overlap between actin and myosin affects the force of contraction.

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16
Q

What are the classes of skeletal muscle fibers?

A

The classes of skeletal muscle fibers include Type I (slow oxidative) and Type II (fast glycolytic), with Type II further divided into Type IIa and Type IIx.

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17
Q

What is a motor unit?

A

A motor unit consists of a motor neuron and all the muscle fibers it innervates, with size affecting muscle control.

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18
Q

What is muscle tone?

A

Muscle tone refers to the small amount of tension present in a relaxed muscle.

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19
Q

What are the types of contractions?

A

The types of contractions include isotonic (concentric and eccentric) and isometric.

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20
Q

What is muscle fatigue?

A

Muscle fatigue is caused by various factors that contribute to a decline in a muscle’s ability to generate force.

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21
Q

What is excess postexercise oxygen consumption (EPOC)?

A

EPOC refers to the physiological processes that contribute to recovery after exercise.

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22
Q

What is smooth muscle?

A

Smooth muscle is found in the walls of internal organs, responsible for involuntary movements.

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23
Q

What are muscle actions and terminology?

A

Muscle actions include terms like ‘abductor’ (pulls away from the midline) and ‘levator’ (raises a body part), each with specific descriptions.

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24
Q

What are muscle origins and insertions?

A

The origin of a muscle is typically more stationary, while the insertion is the more mobile attachment.

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25
Q

What are the components of a lever system?

A

A lever system consists of four components: the lever, the force, the load, and the fulcrum.

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26
Q

Describe the structural differences between skeletal, cardiac, and smooth muscle tissues.

A

Skeletal muscle is striated, multinucleated, and voluntary; cardiac muscle is striated, uninucleated, branched, and involuntary; smooth muscle is non-striated, uninucleated, and involuntary.

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27
Q

Explain how the sliding filament mechanism results in muscle contraction.

A

The sliding filament mechanism involves myosin heads attaching to actin filaments and pulling them towards the center of the sarcomere, resulting in muscle contraction.

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28
Q

What is the role of calcium ions in excitation-contraction coupling?

A

Calcium ions bind to troponin, causing tropomyosin to shift and expose the myosin-binding sites on actin, initiating contraction.

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29
Q

Outline the sequence of events that occur at the neuromuscular junction.

A

An action potential triggers the release of acetylcholine (ACh) into the synaptic cleft, which binds to receptors on the motor end plate, causing depolarization.

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30
Q

What are the three primary energy sources used by muscle fibers during contraction?

A

The three primary energy sources are immediate (stored ATP and creatine phosphate), glycolytic (anaerobic breakdown of glucose), and oxidative (aerobic metabolism).

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31
Q

How does creatine phosphate contribute to muscle energy supply?

A

Creatine phosphate donates a phosphate group to ADP, quickly regenerating ATP for short bursts of muscle activity.

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32
Q

Explain the difference between unfused and fused tetanus.

A

Unfused tetanus allows partial relaxation between stimuli, while fused tetanus results in a smooth, sustained contraction without relaxation.

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33
Q

Describe the length-tension relationship in muscle contraction.

A

A muscle generates maximum force at an optimal length, allowing for the greatest number of crossbridge formations.

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34
Q

What are the key differences between Type I and Type II muscle fibers?

A

Type I fibers are slow oxidative and fatigue-resistant, while Type II fibers are fast glycolytic and fatigue quickly.

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35
Q

How does EPOC contribute to post-exercise recovery?

A

EPOC restores metabolic conditions to resting levels, replenishing oxygen stores and converting lactic acid to glucose.

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36
Q

What is actin?

A

Actin is a protein that forms the thin filaments in muscle fibers, containing myosin-binding sites for contraction.

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37
Q

What is acetylcholine (ACh)?

A

Acetylcholine is a neurotransmitter released at the neuromuscular junction that initiates muscle contraction.

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38
Q

What is an action potential?

A

An action potential is a rapid change in the membrane potential of a cell, triggered by depolarization.

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39
Q

What is the A band?

A

The A band is the dark band in a sarcomere that contains the entire length of the thick filaments.

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40
Q

What is cardiac muscle?

A

Cardiac muscle is a type of striated muscle found in the heart, responsible for pumping blood, and is involuntary.

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41
Q

What is creatine phosphate?

A

Creatine phosphate is a high-energy molecule stored in muscle cells that quickly regenerates ATP.

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42
Q

What is depolarization?

A

Depolarization is a change in the membrane potential to a less negative value, increasing the likelihood of an action potential.

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43
Q

What is elasticity?

A

Elasticity is the ability of a muscle fiber to return to its original length after being stretched.

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44
Q

What is endomysium?

A

Endomysium is the extracellular matrix that surrounds individual muscle fibers.

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45
Q

What is epimysium?

A

Epimysium is the connective tissue layer that surrounds the entire muscle.

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46
Q

What is excitability?

A

Excitability is the ability of a muscle fiber to respond to stimuli, such as nerve impulses.

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47
Q

What is excitation-contraction coupling?

A

Excitation-contraction coupling is the sequence of events linking the action potential to the sliding of myofilaments.

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48
Q

What is extensibility?

A

Extensibility is the ability of a muscle fiber to be stretched beyond its resting length.

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49
Q

What is a fascicle?

A

A fascicle is a bundle of muscle fibers surrounded by perimysium.

50
Q

What is a fulcrum?

A

A fulcrum is the fixed point around which a lever pivots.

51
Q

What is fused tetanus?

A

Fused tetanus is a smooth, sustained muscle contraction with no relaxation between stimuli.

52
Q

What is glycolysis?

A

Glycolysis is the anaerobic breakdown of glucose to produce ATP.

53
Q

What is the H zone?

A

The H zone is the region in the middle of the A band of a sarcomere that contains only thick filaments.

54
Q

What is the I band?

A

The I band is the light band in a sarcomere that contains only thin filaments.

55
Q

What is insertion?

A

Insertion is the attachment of a muscle tendon to the more movable bone or structure.

56
Q

What is isometric contraction?

A

Isometric contraction is a muscle contraction in which the muscle length does not change.

57
Q

What is isotonic contraction?

A

Isotonic contraction is a muscle contraction in which the muscle length changes while the tension remains constant.

58
Q

What is the latent period?

A

The latent period is the time between the arrival of a stimulus and the beginning of muscle contraction.

59
Q

What is a lever?

A

A lever is a rigid structure that pivots around a fulcrum.

60
Q

What is a motor end plate?

A

The motor end plate is the specialized region of the muscle fiber’s sarcolemma that forms the neuromuscular junction.

61
Q

What is a motor unit?

A

A motor unit is a single motor neuron and all the muscle fibers it innervates.

62
Q

What is muscle fatigue?

A

Muscle fatigue is a decline in the ability of a muscle to generate force.

63
Q

What is muscle tone?

A

Muscle tone is the resting tension in a muscle.

64
Q

What is a myofibril?

A

A myofibril is a cylindrical structure within a muscle fiber composed of sarcomeres arranged in series.

65
Q

What are myofilaments?

A

Myofilaments are the protein filaments (actin and myosin) that make up the sarcomere.

66
Q

What is myosin?

A

Myosin is a protein that forms the thick filaments in muscle fibers, with heads that bind to actin and generate force.

67
Q

What is the neuromuscular junction (NMJ)?

A

The neuromuscular junction is the synapse between a motor neuron and a muscle fiber.

68
Q

What is the origin of a muscle?

A

The origin of a muscle is the attachment of a muscle tendon to the more stationary bone or structure.

69
Q

What is oxidative metabolism?

A

Oxidative metabolism is the aerobic breakdown of glucose, fats, and proteins to produce ATP.

70
Q

What is perimysium?

A

Perimysium is the connective tissue layer that surrounds a fascicle.

71
Q

What is repolarization?

A

Repolarization is the return of the membrane potential to its resting value after depolarization.

72
Q

What is resting membrane potential?

A

Resting membrane potential is the voltage difference across the plasma membrane of a cell when it is not being stimulated.

73
Q

What is the sarcolemma?

A

The sarcolemma is the plasma membrane of a muscle fiber.

74
Q

What is the sarcoplasm?

A

Sarcoplasm is the cytoplasm of a muscle fiber.

75
Q

What is the sarcoplasmic reticulum (SR)?

A

The sarcoplasmic reticulum is the endoplasmic reticulum of a muscle fiber, which stores and releases calcium ions.

76
Q

What is skeletal muscle?

A

Skeletal muscle is a type of striated muscle attached to bones, responsible for voluntary movements.

77
Q

What is the sliding filament mechanism?

A

The sliding filament mechanism is the process by which actin and myosin filaments slide past each other, shortening the sarcomere and causing muscle contraction.

78
Q

What is smooth muscle?

A

Smooth muscle is a type of muscle found in the walls of internal organs, responsible for involuntary movements.

79
Q

What is the synaptic cleft?

A

The synaptic cleft is the gap between the motor neuron and the muscle fiber at the neuromuscular junction.

80
Q

What is titin?

A

Titin is a structural protein in the sarcomere that provides elasticity and stability.

81
Q

What are transverse tubules (T-tubules)?

A

Transverse tubules are invaginations of the sarcolemma that transmit action potentials deep into the muscle fiber.

82
Q

What is a triad?

A

A triad is the structure formed by a T tubule with a sarcoplasmic reticulum (SR) known as the terminal cisternae on either side.

83
Q

What is tropomyosin?

A

Tropomyosin is a regulatory protein that covers the myosin-binding sites on actin in a relaxed muscle fiber.

84
Q

What is troponin?

A

Troponin is a regulatory protein that binds to calcium ions, causing tropomyosin to shift and expose the myosin-binding sites on actin.

85
Q

What is a twitch?

A

A twitch is a single contraction and relaxation cycle in a muscle fiber.

86
Q

What are Type I fibers?

A

Type I fibers are slow oxidative muscle fibers that are fatigue-resistant and primarily use aerobic metabolism.

87
Q

What are Type II fibers?

A

Type II fibers are fast glycolytic muscle fibers that fatigue quickly and primarily use anaerobic metabolism.

88
Q

What is unfused tetanus?

A

Unfused tetanus is a sustained muscle contraction with partial relaxation between stimuli.

89
Q

What are voltage-gated channels?

A

Voltage-gated channels are ion channels that open or close in response to changes in membrane potential.

90
Q

What is ponin?

A

A regulatory protein that binds to calcium ions, causing tropomyosin to shift and expose the myosin-binding sites on actin.

91
Q

What is a twitch?

A

A single contraction and relaxation cycle in a muscle fiber.

92
Q

What are Type I Fibers?

A

Slow oxidative muscle fibers that are fatigue-resistant and primarily use aerobic metabolism.

93
Q

What are Type II Fibers?

A

Fast glycolytic muscle fibers that fatigue quickly and primarily use anaerobic metabolism.

94
Q

What is unfused tetanus?

A

A sustained muscle contraction with partial relaxation between stimuli.

95
Q

What is voltage?

A

A difference in electrical potential.

96
Q

What are voltage-gated channels?

A

Ion channels that open or close in response to changes in membrane voltage.

97
Q

What is a Z Disc?

A

The boundary of a sarcomere to which thin filaments are anchored.

98
Q

What are the three types of muscle tissue?

A

Skeletal, cardiac, and smooth muscle.

99
Q

What are the properties of muscle cells?

A

Contractility, excitability, extensibility, elasticity, conductivity, and distensibility.

100
Q

What is the structure of skeletal muscle fibers?

A

Long, cylindrical cells containing multiple nuclei, with a plasma membrane called the sarcolemma and cytoplasm called the sarcoplasm.

101
Q

What is the sarcoplasmic reticulum (SR)?

A

A specialized endoplasmic reticulum that stores and releases calcium ions.

102
Q

What is the functional unit of muscle contraction?

A

The sarcomere.

103
Q

What occurs during the sliding-filament mechanism of contraction?

A

Thin filaments slide past thick filaments, shortening the sarcomere.

104
Q

What is the resting membrane potential of muscle fibers?

A

About -90 mV.

105
Q

What is the neuromuscular junction (NMJ)?

A

The synapse between a motor neuron and a muscle fiber.

106
Q

What is excitation-contraction coupling?

A

The process by which an action potential leads to muscle contraction.

107
Q

What is required for muscle contraction?

A

ATP.

108
Q

What is a motor unit?

A

A single motor neuron and all the muscle fibers it innervates.

109
Q

What happens during muscle relaxation?

A

The motor neuron stops releasing ACh, and calcium ions are pumped back into the sarcoplasmic reticulum.

110
Q

What causes muscle fatigue?

A

Depletion of key metabolites, accumulation of certain chemicals, and inadequate oxygen.

111
Q

What is the role of smooth muscle?

A

Involved in peristalsis, forming sphincters, and regulating the flow of materials through hollow organs.

112
Q

What is the significance of intercalated discs in cardiac muscle?

A

They allow cardiac muscle cells to contract as a unit.

113
Q

Describe the three layers of connective tissue surrounding a skeletal muscle, from the innermost to the outermost.

A

The layers of connective tissue are: endomysium (surrounds each muscle fiber), perimysium (surrounds fascicles), and epimysium (surrounds the entire muscle).

114
Q

Explain the difference between the origin and insertion of a muscle.

A

The origin is the more stationary attachment point of a muscle to a bone, while the insertion is the more mobile attachment point.

For example, the biceps brachii’s origin is the scapula, and its insertion is the radius.

115
Q

What are the four muscles of mastication?

A

The muscles of mastication are the masseter, temporalis, medial pterygoid, and lateral pterygoid.

116
Q

What are the four rotator cuff muscles? What is their general function?

A

The rotator cuff muscles are the supraspinatus, infraspinatus, teres minor, and subscapularis. Their general function is to stabilize the shoulder joint.

117
Q

List two muscles that cause plantar flexion and dorsiflexion of the foot.

A

The gastrocnemius and soleus muscles cause plantar flexion, while the tibialis anterior causes dorsiflexion.

118
Q

What are the muscles of the hamstring group?

A

The hamstring group consists of the biceps femoris, semitendinosus, and semimembranosus muscles.

119
Q

What are the three muscles that make up the erector spinae group?

A

The erector spinae group consists of the iliocostalis, longissimus, and spinalis muscles.

120
Q

Describe the PRICE method for treating muscle strains.

A

The PRICE method stands for Protection, Rest, Ice, Compression, and Elevation. It’s used to reduce inflammation and promote healing in muscle strains.

121
Q

Define agonist, antagonist, and synergist in terms of muscle action.

A

An agonist is the prime mover, an antagonist opposes the agonist, and a synergist assists the agonist to produce movement.

122
Q

Explain what a lever system is, naming its four components.

A

A lever system has four components: lever, force, load, and fulcrum. Muscles utilize lever systems to produce movement.