Unit 1.6 - Genetic information is copied and passed on to daughter cells Flashcards
What does cell division start from?
1 cell
What’s cell division essential for?
The development of ALL organisms
What’s essential for the development of all organisms?
Cell division
What are the two types of cell division?
Mitosis and meiosis
What does mitosis form?
All cells (apart from gametes)
What does meiosis form?
Gametes
Why is cell division important for maintaining the body?
Cells have a lifespan and don’t last forever
List the steps involved in a cell’s life cycle
Start
G1
R
S
G2
What are G1, R, S and G2 steps in?
Cell division
What is cell division to a cell’s entire life?
Only a small section
What’s the starting point of a cell’s lifespan?
Where a new cell has formed via cell-division
What happens at the G1 stage of a cell’s lifespan?
Cell is increasing in size
At which stage in a cell’s lifespan is it increasing in size?
G1
What happens at the R stage of a cell’s lifespan?
Cell decides whether to remain in G1 or to replicate
At which stage in a cell’s life cycle does a cell decide whether to replicate or remain in G1?
R
What do most cells do once they react the R stage of its life cycle? Why?
Remain in G1 once they’ve specialised, as they’re unlikely to divide again
What are most cells by the G1 stage and what does this mean?
Specialised, meaning they’re unlikely to divide again
What happens at the S stage of the cells lifecycle?
DNA replciation
Where does DNA replication occur in a cell’s life cycle?
S stage
What happens at the G2 stage of a cell’s lifecycle?
It synthesises organelles (prepares for cell division)
At which stage in a cell’s life cycle does it synthesise organelles and prepare for cell division?
G2
From which stages in DNA replication is interphase?
G1-G2
What’s the period from G1-G2 in a cell’s lifecycle known as?
Interphase
What can we see under a microscope during interphase?
Nothing -no visible changes
In which stage of a cell’s life cycle are there no visible changes?
Interphase
List 4 events of interphase
Protein synthesis
DNA replication (s)
Synthesis of new organelles
Increase in cell size
When do the following events all occur?
Protein synthesis, DNA replication, synthesis of new organelles, increased in cell size
Interphase
Why is it necessary for all of these procedures to take place during interphase?
Following cell division, the cell has half of everything except DNA which is an exact copy
What’s the only thing a cell doesn’t have half of following cell division?
DNA, which is an exact copy
Describe DNA during interphase
In the nucleus in the form of chromatin
During which stage in a cell’s lifespan is the DNA in the nucleus in the form of chromatin?
Interphase
What does chromatin do as we enter into mitosis?
Condenses to form chromosomes
What condenses to form chromosomes when entering into mitosis?
Chromatin
When does chromatin condense to form chromosomes?
Entering into mitosis
How many pairs of chromosomes are in every human cell?
23
What do we have 23 of and where?
PAIRS of chromosomes in our cells
What are the only cell’s in the body that don’t have 23 pairs of chromosomes? How many do they have?
Gametes, which have 23 EACH
How many chromosomes are in gametes and how does this make them different?
23 each, whereas all of the other human cells have 23 pairs
What do chromosomes exist as? What does this mean for them?
Homologous pairs, so they have very similar shapes
What exist as homologous pairs?
Chromosomes
What are the only chromosomes which don’t exist as homologous pairs?
X and Y
What do X and Y not exit as?
Homologous pairs of chromosomes
Why do chromates exist in homologous pairs?
The first cell was fertilised by an egg containing 1/2 the necessary chromosomes, and a sperm cell containing the other 1/2, together forming 23 pairs
What’s similar between two chromosomes in a homologous pair?
They have the exact same genes in the exact same locations which code for the same thng
What have the exact same genes?
Two chromosomes in a pair
How are the genes in chromosome pairs different?
They’re not - they could be different alleles of the gene though (e.g - BLUE eyes, not just eye colour)
What could be different alleles? Give an example
Genes that code for something specific
E.g - gene for eye colour
Different alleles = brown or blue or green eyes
Karotype
The preparation of the complete set of metaphase chromosomes in a cell
The preparation of the complete set of metaphase chromosomes in a cell
Karotype
Which phase are the chromosomes in in a Karotype?
Metaphase
What do chromosomes contain?
Long sections of DNA, proteins and a small amount of RNA
What do genes run along the length of?
Chromosomes
What run along the length of chomomes?
Genes
When are chromosomes visible?
On the onset of cell division
What are only divisible on the onset of cell division?
Chromosomes
How is DNA packed inside the nucleus?
Wrapped around histone protein molecules, which are condensed together to form chromatin fibres
What are condensed together to form chromatin fibres?
DNA wrapped around histone protein molecules
Chromatids
An identical thread of DNA from a copy itself
An identical thread of DNA from a copy of tself
Chromatid
What are joined together to form a chromosome and by what?
Chromatids, by a centromere
What does a centromere do?
Join chromatids together to form a chromosome
What do chromatids do?
Join together to form a chromosome
When does each DNA molecule make a copy of itself?
Shortly before cell division
What does DNA do shortly before cell division?
Makes a copy of itself
What happens to chromatids when a cell divides?
Chromatids are pulled apart into the new cells, ensuring that the new cell gets an exact copy of all of the genes on the DNA molecule
Draw and label a chromosome
(Check notes)
What are the 4 stages of mitosis?
Prophase
Metaphase
Anaphase
Telophase
Draw and label the prophase of mitosis
(Check notes)
Draw and label the metaphase of mitosis
(Check notes)
Draw and label the anaphase of mitosis
(Check notes)
Draw and label the telophase of mitosis
(Check notes)
What’s the longest stage of mitosis and what can be done therefore?
Prophase
Can be split into prophase and prometaphase
What happens during the prophase of mitosis?
The DNA (chromatin) condenses to form chromosomes
Chromatids become visible
In animal cells, the centrioles move to opposite poles of the cell
Protein microtubules form from each centriole and the spindle develops, extending from pole to pole
Towards the end, the nuclear membrane disintegrates and the nucleolus dissappears
Pairs of chromatids can clearly be seen lying free in the cytoplasm
In what type of cell alone do centrioles move to the opposite poles of the cell?
Animal cells
What do animal cells do during the prophase?
The centrioles move to opposite poles of the cell
In which stage of mitosis do chromatids become visible?
Prophase
What become visible during the prophase of mitosis?
Chromatids
When can pairs of chromatids be seen clearly in the cytoplasm?
Prophase
What forms from each centriole to the other during prophase?
Protein microtubules
At which stage does the nuclear membrane of a cell disintegrate and its nucleolus disappear?
Towards the end of the prophase
What do the chronometer attach to during mitosis and with what?
The spindle fibres, at the centromere
What happens during the metaphase of mitosis?
The chromosomes arrange themselves at the centre or equator of the spindle
Chromosomes become attached to the spindle fibres at the centromere
Contraction of the spindle fibres draws the individual chromatids apart
What type of fibres are the spindle fibres?
Contractile proteins
Where do chromosomes arrange themselves and during which stage of mitosis?
At the equator or centre of the spindle during the metaphase
What draws the individual chromatids apart during the metaphase of mitosis?
Contraction of the spindle fibres
What happens during the anaphase of mitosis?
Centromere splits
Spindle fibres contract and shorten
Chromatids separate and are pulled to opposite poles of the cell
Centromeres lead the way
Which phase of mitosis occurs fastest?
The anaphase
How are chromatids separated during mitosis and in which stage?
When the spindle fibres contract and shorten during the anaphase
What lead the way during the anaphase of mitosis?
Centromeres
Cytokinesis
Cell splitting - divide the cytoplasm of the parental cell into two daughter cells
Cell splitting
Cytokinesis
When does cytokinesis occur during mitosis?
At the telophase
What happens during the telophase of mitosis?
Chromatids have reached the poles and are referred to as chromosomes again
Chromosomes uncoil and lengthen
Spindle breaks down
Nucleolus reappears
Nuclear membrane reforms
When are chromatids referred to as chromosomes again during mitosis?
When they’ve reached the poles during the telophase
In which stage of mitosis does the spindle break down?
Telophase
During which stage of mitosis does the nucleolus reappear?
Telophase
During which stage of mitosis does the nuclear membrane reform?
Telophase
What do chromosomes do during the telophase of mitosis?
Uncoil and lengthen
Draw the stages of mitosis as they would appear under a microscope
(Check notes)
What’s proportional to the % of cells in each stage of cell division?
The length of the stage
What’s proportional to the length of the stage during mitosis?
The % of cells in each stage of the cell cycle
Where’s a good place to find dividing cells?
The meristem (root tip)
Root tip
Meristem