Unit 1 terminology

Question 1

Define: Trade name

Answer 1

The name given to a drug by the pharmaceutical company; it is protected by a trademark and used by the company for marketing the drug

Question 2

Define: pharmacy

Answer 2

the professional discipline dealing with the preparation and dispensing medication

Question 3

Define: Median toxic dose

Answer 3

Drug dose that elicits a toxic response in 50% of the patients it is tested on

Question 4

Define: Median lethal dose

Answer 4

The drug dose that causes death in 50% of animals its tested on

Question 5

Define: Therapeutic index

Answer 5

Ratio used to determine safety of a drug. The larger the safer.
Toxic median dose divided by the median effective dose.

Question 6

Define: Chemical Name

Answer 6

A drug name that is derived from the specific chemical structure of the compound.

Question 7

Define: Generic Name

Answer 7

Name applied to a drug that is not protected by a trademark, often shortened chamical name

Question 8

Define: Bioavailability

Answer 8

The extent to which a drug reaches systemic circulation

Question 9

Define: over the counter drugs

Answer 9

drugs that can be purchased without a prescription

Question 10

Define: Buccal

Answer 10

Referring to cheek. Drugs that are administered buccally are placed between the cheek and gum

Question 11

Define: Potency

Answer 11

The strength of a drug

Question 12

Define: Pharmacogenetics

Answer 12

The study of how genetic variation can affect drug response

Question 13

Define: Parenteral administration

Answer 13

Administration of drugs other than alimentary canal, injection, transversally, topically

Question 14

Define: Pharmacokinetics

Answer 14

The study of how drugs move through the body

Question 15

Define: Dose response Curve

Answer 15

The relationship between dose and reaction

Question 16

Define: Pharmacodynamics

Answer 16

The study of how drugs affect the body

Question 17

Define: Controlled substance

Answer 17

Drugs designated by the government as having increased potential for abuse and illegal use

Question 18

Define: Volume of distribution (Vd)

Answer 18

A ratio used to estimate the amount of a drug in the body relative to fluid volume of the body. Amount of drug divided by plasma concentration.

Question 19

Define: First pass effect

Answer 19

When drugs absorbed by stomach and intestine must first pass through the liver

Question 20

Define: Orphan drugs

Answer 20

Drugs designed and approved to treat rare diseases

Question 21

Define: Pharmacotherapeutics

Answer 21

The study of how drugs are used in preventing and treating disease

Question 22

Define: Off-label prescribing

Answer 22

Drug prescribed to treat a prescription other than those approved by FDA

Question 23

Define: Sublingual

Answer 23

Under the tongue. Enter body via venous drainage

Question 24

Define: Proton pump

Answer 24

An enzyme that moves hydrogen across a cell membrane. “proton pump inhibitors” reduce the effects of stomach acid

Question 25

Define: Median effective dose

Answer 25

Drug dose that produces a specific therapeutic response in 50 percent of the patients it is tested on

Question 26

Define: Nonproprietary name

Answer 26

Synonym for generic name

Question 27

Define: Intrathecal

Answer 27

administration via a sheath, usually injected into the subarachnoid space

Question 28

Define: toxicology

Answer 28

The study of harmful effects of drugs and chemicals

Question 29

Define: Enteral Administration

Answer 29

Administration of drugs by way of the alimentary canal