Unit 1 Section 2: Cell membranes - the basics Flashcards
Purpose of cell membrane
controls which substances enter and leave the cell (partially permeable) also allowing recognition by other cells
purpose of membranes around organelles
dividing the main cell into different compartments, e.g. substances needed for respiration are kept inside the mitochondria by it’s outer membrane
some organelle membranes are folded to…
increase surface area and making chemical reactions more efficient, e.g. the inner membrane of mitochondria contains enzymes for respiration, it has a large surface area increasing the number of enzymes present making respiration more efficient
vesicles
membranes can form vesicles to transport substances around the cell, e.g. proteins are transported between the RER and Golgi apparatus during protein synthesis, in vesicles
membranes within the cell are also..
Partially permeable to select what enters and leaves the organelle, e.g. RNA can leave the nucleus via the nuclear membrane(envelope) however DNA is too large
all membranes mainly compose of…
lipids(phospholipids), proteins and carbohydrates.
cell surface membrane model is called
fluid mosaic model
the fluid mosaic model
phospholipid molecules form a continuous double layer (bilayer). the phospholipids are moving and so the bilayer is fluid. Protein molecules are scattered through the bilayer sometimes with a polysaccharide chain (carbohydrate) attached- these are called glycoproteins and glycolipids when attached to a lipid. cholesterol is also present within the bilayer
phospholipids
form a barrier to water soluble (dissolved) substances.
- have a phosphate, hydrophilic (attracts water) head.
- have a lipid, hydrophobic (repels water) tail
- centre of bilayer is hydrophobic so water soluble substances- such as ions & polar molecules- cannot difuse through it.
- small non-polar substances and water can diffuse through the membrane
cholesterol
- gives the membrane stability
- type of fat that’s present in all cell membranes (except bacteria)
- fits between the phohpholipids
- binds to hydrophobic tails forcing them to pach closely together. this makes the membrane less fluid and more stable.
- also has hydrophobic region so provides further barrier against polar substances
Proteins
- Control what enters and leaves the cell
- some form channels
- others are called carrier
- react as receptors in cell signalling, when a molecule binds to the protein a chemical reaction is triggered inside the cell
glycol lipids/proteins
- stabalise the membrane by forming hydrogen bonds with surrounding water
- act as receptors for messenger molecules
- antigens involved in self-recognition
temperature
affects how much the phospholipids can move affecting the membrane structure.
below 0’C
phospholipids don’t have much energy so they can’t move very much, paked closely together so membrane becomes rigid. carrier (& channel) proteins denature, increasing permeability. Ice crystals may form and peirce thhe membrane making it permeable when it thaws.
0-45’C
phospholipids can move and aren’t packed as tightly. increased permeability as phospholipids move about more