Unit 1 Section 2: Cell membranes and signalling Flashcards
importance of cell signalling
cells need communicate to control processes inside the body and respond to changes in the environment
cell signalling starts…
when one cell releases a messenger molecule such as a hormone. this travels to another cell, where it is detected because it binds to a receptor on the cell membrane. this triggers a change in the cell, e.g. chemical signals sent off.
membrane bound proteins…
act as receptors for messenger molecules
receptor proteins
have specific shapes so that only messenger molecules with a complementary shape can bind to them. different cells have different types of receptor, meaning they respond to different messenger molecules. when a cell responds to a particular molecule it is called the TARGET CELL. cells can have many combinations of receptor cells they are not restricted to 1.
examples of hormone messenger molecules
- Glucagon is a hormone released when there isn’t enoughglucose in the blood. It binds to receptors on liver cells causing liver cells to break down stores of glycogen to glucose.
- FSH hormone is released by the pituitary gland during the menstrual cycle. It binds wuth receptors on cells in the ovaries, causing an egg to mature, ready for ovulation.
- FSH can also bind to cells in the testes to initiate the production of sperm.
role of drugs
some drugs also bind to receptors in cell membranes. they either trigger a response or block a receptor preventing it from working.
drug examples
- Morphine binds to the same recepters an endorphins and triggers a reduction in pain signals that are sent.
- Antihistamines block histamine receptors on the surface of cells preventing histamine from binding, therefore reducing inflammation.
define antagonistic molecules
a molecule that blocks the action of another.