Unit 1 Flashcards

Lectures 1-4; General principles of addiction

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1
Q

Addiction is not

A

drug dependence
drug abuse
bad habit

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2
Q

Addiction is

A

loss of control
catastrophic consequences
decrease in pleasure

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3
Q

Addiction (definition)

A

Brain disorder defined as a chronic, relapsing disorder characterized by compulsive drug-seeking and use despite adverse consequences

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4
Q

Why do we consider addiction a disease

A

it is treatable, preventable, modifies biology, and has genetic factors

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5
Q

iRISA stands for

A

Impaired response inhibition & salience attribution

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6
Q

iRISA process

A

take drug – craving – binge (loss of control) – withdrawl – relapse

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7
Q

Cravings are induced by

A

triggers (e.g. stress)

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8
Q

Impairments in which six brain networks

A

Executive network
salience network
reward network
habit network
self-directed network
memory network

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9
Q

Impaired decision-making is associated with which part of the brain?

A

the Prefrontal cortex

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10
Q

After how long in recovery did patients show improvements in cognitive control/flexibility by increased accuracy on WST

A

after 6-months clean

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11
Q

What is the disease model debate?

A

Proponents emphasize that it can help relieve individuals addicted to substances of debilitating feelings of guilt
Treatment including harm reduction and policy initiatives will receive attention and funding
Society will benefit if addicted individuals are treated medically

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12
Q

Why is free will an object of debate?

A

addiction could compromise an individual’s ability to choose freely between alternative courses of action

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13
Q

Risk factor (definition)

A

biological, psychological, family, community, and SE factors that are associated with an increased likelihood of negative consequences

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14
Q

Protective factor (definition)

A

characteristics associated with a decreased likelihood of negative outcomes or that reduce the potency of a risk factor

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15
Q

Domains of risk/protective factors

A

Individual
Family
Peer
Community

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16
Q

How does green space serve as a protective factor?

A

development of better stress-processing ability and less need to self-medicate

17
Q

What aspects of the family environment can serve as protective factors?

A

Authoritative and emotionally responsive parenting approach
Two parent home + involvement
Higher parent education and SE status
Consistency + dependability

18
Q

What aspects of the prenatal environment serve as risk factors?

A

prenatal anxiety is often associated with child externalizing difficulties and verbal IQ – leads to mental health issues and a higher desire to self-medicate

19
Q

What aspects of the economic environment can serve as risk factors?

A

young children with income below the poverty line score lower on measures of prefrontal functioning (decision-making + attention)

20
Q

Heritability is responsible for how much of the population’s variability in developing an addiction.

A

40-60%

21
Q

Polymorphism (definition)

A

genetic variation

22
Q

If your transmitter receptor is a variant when you release the transmitter that affects that receptor…

A

the effect may be different

23
Q

There are over ______________ that lead to variant proteins that are associated with vulnerability to addiction

A

100 polymorphisms

24
Q

Individual protective factors

A

perception of substance abuse
affiliating with a prosocial group
secure attachment
emotional regulation skills
temperament
self-competence
healthy coping skills