Unit 1 Flashcards
Lectures 1-4; General principles of addiction
Addiction is not
drug dependence
drug abuse
bad habit
Addiction is
loss of control
catastrophic consequences
decrease in pleasure
Addiction (definition)
Brain disorder defined as a chronic, relapsing disorder characterized by compulsive drug-seeking and use despite adverse consequences
Why do we consider addiction a disease
it is treatable, preventable, modifies biology, and has genetic factors
iRISA stands for
Impaired response inhibition & salience attribution
iRISA process
take drug – craving – binge (loss of control) – withdrawl – relapse
Cravings are induced by
triggers (e.g. stress)
Impairments in which six brain networks
Executive network
salience network
reward network
habit network
self-directed network
memory network
Impaired decision-making is associated with which part of the brain?
the Prefrontal cortex
After how long in recovery did patients show improvements in cognitive control/flexibility by increased accuracy on WST
after 6-months clean
What is the disease model debate?
Proponents emphasize that it can help relieve individuals addicted to substances of debilitating feelings of guilt
Treatment including harm reduction and policy initiatives will receive attention and funding
Society will benefit if addicted individuals are treated medically
Why is free will an object of debate?
addiction could compromise an individual’s ability to choose freely between alternative courses of action
Risk factor (definition)
biological, psychological, family, community, and SE factors that are associated with an increased likelihood of negative consequences
Protective factor (definition)
characteristics associated with a decreased likelihood of negative outcomes or that reduce the potency of a risk factor
Domains of risk/protective factors
Individual
Family
Peer
Community
How does green space serve as a protective factor?
development of better stress-processing ability and less need to self-medicate
What aspects of the family environment can serve as protective factors?
Authoritative and emotionally responsive parenting approach
Two parent home + involvement
Higher parent education and SE status
Consistency + dependability
What aspects of the prenatal environment serve as risk factors?
prenatal anxiety is often associated with child externalizing difficulties and verbal IQ – leads to mental health issues and a higher desire to self-medicate
What aspects of the economic environment can serve as risk factors?
young children with income below the poverty line score lower on measures of prefrontal functioning (decision-making + attention)
Heritability is responsible for how much of the population’s variability in developing an addiction.
40-60%
Polymorphism (definition)
genetic variation
If your transmitter receptor is a variant when you release the transmitter that affects that receptor…
the effect may be different
There are over ______________ that lead to variant proteins that are associated with vulnerability to addiction
100 polymorphisms
Individual protective factors
perception of substance abuse
affiliating with a prosocial group
secure attachment
emotional regulation skills
temperament
self-competence
healthy coping skills