UGT Review Flashcards

1
Q

what does the UGT enzyme do

A

glucoronidation

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2
Q

Valproic Acid

UGT Inducer, Substrate or Inhibitor?

A

Inhibitor

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3
Q

Lamotrigine

UGT Inducer, Substrate or Inhibitor?

A

substrate + inducer

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4
Q

lorazepam

UGT Inducer, Substrate or Inhibitor?

A

major substrate

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5
Q

carbamazepine

UGT Inducer, Substrate or Inhibitor?

A

inducer

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6
Q

oxazepam

UGT Inducer, Substrate or Inhibitor?

A

substrate

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7
Q

NSAIDs

UGT Inducer, Substrate or Inhibitor?

A

major inhibitor

substrate

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8
Q

Tacrolimus

UGT Inducer, Substrate or Inhibitor?

A

inhibitor

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9
Q

Morphine

UGT Inducer, Substrate or Inhibitor?

A

substrate

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10
Q

olanzapine

UGT Inducer, Substrate or Inhibitor?

A

substrate

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11
Q

FGAs and SGAs

UGT Inducer, Substrate or Inhibitor?

A

substrates

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12
Q

furosemide

UGT Inducer, Substrate or Inhibitor?

A

substrate

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13
Q

diclofenac

UGT Inducer, Substrate or Inhibitor?

A

major inhibitor

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14
Q

TCAs

UGT Inducer, Substrate or Inhibitor?

A

substrate

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