Stimulants + Non stimulant ADHD meds Flashcards

1
Q

note–a bunch of stimulant review is in the ADHD section (CADDRA guidelines)

A
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2
Q

list the 3 formulations of amphetamines

A

dexedrine (dextroamphetamine)–> tablets (IR) or spansules (XR)

vyvanse (lisdexamphetamine)

adderall XR (dextropamphetamine)

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3
Q

list the formulations of methylphenidate available

A

Ritalin (IR or SR)

Biphentin

Concerta (OROS)

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4
Q

what assessments should be done before starting ANY stimulant

A

BP, HR

height, weight

(ECG only if cardiac history or other clinical concern)

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5
Q

how quickly should you be adjusting stimulant doses

A

can do every 7 days

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6
Q

side effects of stimulant medications

A

insomnia

irritability (?more with amphetamine rather than methylphenidate)

headache

anxiety

appetite suppression

weight loss

N/V/D

?worsened tics

tachycardia

HTN

growth delay (?1 inch with sustained stimulant use)

**in OSCE, mention cardiac risks/black box warning for monitoring for cardiac risks

**in OSCE, mention risk for diversion and misuse of stimulants

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7
Q

max dose of adderall

A

30mg po daily

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8
Q

max dose of vyvanse

A

60mg po daily

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9
Q

max dose for dexedrine

A

30mg/day for kids

40mg/day for adults

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10
Q

how long does vyvanse last

A

13-14 hours

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11
Q

how long does dexedrine last

A

4 hours for tablets

6-8 hours for spansules

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12
Q

how long does adderall XR last

A

12 hours

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13
Q

how long does ritalin last

A

3-4 hours

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14
Q

what is the max dose of ritalin

A

60mg /day

CADDRA says up to 100mg for adults

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15
Q

how long does biphentin last

A

10-12 hours

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16
Q

how long does concerta last

A

12 hours

must be swallowed whole

17
Q

how long does foquest last

A

up to 16 hours

18
Q

max dose of biphentin

A

60mg/day for kids

80mg/day for adults

19
Q

max dose of concerta

A

54mg/day for kids

72mg/day for adults

20
Q

other than ADHD, what is an indication for ritalin

A

depression in the medically unwell

21
Q

what is a black box warning/concern with atomoxetine

A

warn of risk of SI with atomoxetine

22
Q

you should use caution with atomoxetine in the setting of which medical comorbidity

A

asthma

23
Q

side effects of atomoxetine

A

tachycardia

HTN

anxiety

N/V/D

irritability

headache

weight loss

doesnt worsen tics

24
Q

in which population might atomoxetine be particularly useful

A

those with SUD history

cant be diverted/abused

25
Q

max dose of atomoxetine

A

1.4mg/kg/day

or 100mg/day

26
Q

what is the mechanism of atomoxetine

A

selective norepinephrine reuptake inhibitor

27
Q

max dose of guanfacine

A

4mg/day in kids

7mg/day in adults

28
Q

max dose of clonidine

A

1.2mg/day

29
Q

guanfacine is first line for what disorder

A

tics

30
Q

side effects of guanfacine, clonidine

A

drowsiness

dizziness

fatigue

bradycardia

syncope

hypotension

dry mouth/eyes

nausea

constipation

31
Q

list indications for modafinil

A

1st line for hypersomnolence disorder and narcolepsy

2nd line for MDD adjunct

3rd line for ADHD

used for fatigue caused by cancer, MS, OSA

32
Q

is modafinil recommended in peds

A

no