UGIB Flashcards
UGIB
Bleeding into the lumen of the proximal GI tract, proximal to the ligament of Treitz
UGIB signs and symptoms
Hematemesis, melena, syncope, shock, fatigue, coffee-ground emesis,
hematochezia, epigastric discomfort, epigastric tenderness, signs of hypovolemia, guaiac-positive stools
PUD
MC cause of significant UGIB
Bacteria associated w/ PUD
H. pylori
Treatment PUD
MOC - metronidazole, omeprazole, clarithromycin
ACO - ampicillin, clarithromycin, omeprazole
Valentino’s sign
RLQ pain/peritonitis as a result of succus collecting
from a perforated peptic ulcer
Duodenal Ulcers
pain relieves by food
Cause of DU
increased production of gastric acid
DU associated syndrome
Zollinger-Ellison syndrome
DU risk factors
Male gender, smoking, aspirin and other NSAIDs, uremia, Z-E syndrome, H. pylori, trauma, burn injury
DU symptoms
Epigastric pain—burning or aching, usually several hours after a meal (food, milk, or antacids initially relieve pain) Bleeding Back pain Nausea, vomiting, and anorexia ↓ appetite
DU signs
tenderness in epigastric area (possibly) guaiac-positive stool melena hematochezia hematemesis
EGD findings associated w/ rebleeding
Visible vessel in the ulcer crater, recent clot, active oozing
DU medical treatment
PPIs (proton pump inhibitors) or H2 receptor antagonists—heal ulcers in
4 to 6 weeks in most cases
DU indications for surgery
Intractability
Hemorrhage (massive or relentless)
Obstruction (gastric outlet obstruction)
Perforation
Artery involved in bleeding duodenal ulcers
Gastroduodenal artery
Truncal vagotomy
Pyloroplasty
Duodenal perforation
Graham patch (poor candidates, shock, prolonged perforation)
Truncal vagotomy and pyloroplasty incorporating ulcer
Graham patch and highly selective vagotomy
Truncal vagotomy and antrectomy (higher mortality rate, but lowest recurrence rate)
DU intractability
PGV (highly selective
vagotomy)
vagotomy and pyloroplasty
Vagotomy and antrectomy BI or BII (especially if there is a coexistent pyloric/prepyloric ulcer) but associated with a higher mortality
Ulcer operation has the HIGHEST ulcer recurrence
rate and the LOWEST dumping syndrome rate
PGV (proximal gastric vagotomy)
Ulcer operation has
the LOWEST ulcer recurrence rate and the HIGHEST dumping syndrome rate
Vagotomy and antrectomy
Why must you perform a
(pyloroplasty, antrectomy)
after a truncal vagotomy?
Pylorus will not open after a truncal drainage procedure vagotomy
DU with lowest mortality rate
PGV (1/200 mortality), truncal vagotomy and pyloroplasty (1–2/200), vagotomy and antrectomy (1%–2% mortality)
Gastric Ulcers
40–70 years old (older than the duodenal ulcer population)
food increases GU pain
Cause of GU
DECREASED CRYOPROTECTION or gastric
protection (i.e., decreased bicarbonate/ mucous production)
GU associated increased gastric acid
prepyloric
pyloric
coexist w/ DU
GU risk factors
Smoking, alcohol, burns, trauma, CNS tumor/trauma, NSAIDs, steroids, shock,
severe illness, male gender, advanced age
GU symptoms
Epigastric pain
+/-Vomiting, anorexia, and nausea
GU diagnosis
History, PE, EGD with multiple biopsy (r/o gastric cancer)
GU MC location
lesser curvature - 70%
Options for concomitant duodenal and gastric ulcers
Resect (BI, BII) and TRUNCAL VAGOTOMY
Common option for surgical treatment of a PYLORIC gastric ulcer?
Truncal vagotomy and antrectomy (i.e., BI or BII)
Common option for a poor operative candidate
with a perforated gastric ulcer
Graham patch