UC & Crohn's Flashcards
How does IBD present?
Relapsing and remitting Pain Diarrhoea Weight loss Passing blood
How do you investigate to IBD?
Faecal calprotectin
Endoscopy is diagnostic
MRI for fistulas and strictures
Which part of bowel affected in crohs?
Whole thing
Which has skip lesions? Crohn or UC?
Crohsn
Which part pf bowel is most affected by crohns
Terminal ileum
How thick is inflammation in crohn’s?
Full thickness
TRANSMURAL
Leads to stricture and fistula formation
Which is smoking a risk factor for? C or UC?
Crohns
How is Crohn’s managed?
Oral pred or IV hydrocortisone to induce remission
Azathioprine/Methotrexate/Adalimumab is this fails
Azathioprine or mercaptopurine to maintain remission
What surgery can be done in Crohn’s/
If only terminal ileum affected can surgically resect
How deep is inflammation in UC?
Superficial only
Does UC have skip lesions?
NO
What is seen more in faeces in UC?
Blood and mucus
Is smoking a risk factor in UC?
NO
Protective factor
How is remission induced in UC?
AMINOSALYCYLATES (Mesalazine) or Pred if mild
IV hydrocortisone if severe
How is remission maintained in UC?
Mesalazine or azathioprine
