Coeliac Flashcards
1
Q
Which HLA are associated with coeliac?
A
DR2 and 8
2
Q
What are signs of coeliac?
A
Mouth ulcers B12 folate deficiency Fe deficiency Osteoporosis Dermatitis Herpetiformis Peripheral neuropathy
3
Q
How do you diagnose coeliac?
A
NEED TO STILL EAT GLUTEN! tGG (tissue transglutaminase) anti EMA (endomysial ab) anti DPG IgA and IgG Duodenal biopsy showing villous atrophy and crypt hypertrophy
4
Q
What are the criteria for duodenal biopsy in coeliac?
A
Marsh
5
Q
What are biopsy signs in coeliac?
A
Crypt hypertrophy
Villous atrophy
6
Q
How is coeliac managed?
A
GF diet
DEXA
7
Q
What are risks if GF diet not followed?
A
Osteoporosis
Oesophageal, ENT, small bowel cancer
QOL down
8
Q
What are complications of coeliac?
A
Vitamin deficiency Anaemia Osteoporosis Lymphoma NHL
