Malignancy Flashcards
1
Q
What are warning symptoms in Oesophageal cancer (not obvious ones)?
A
GI bleed
Sister Mary Joseph Nodule around umbilicus
Virschow’s (supraclavicular) nodule
2
Q
What are risk factors for gastric cancer?
A
Saly heavy and low veg diet Nitrates Smoking Aspirin genetics HNPCC FAP Juvenile polyposis CDH1 mutations H pylori
3
Q
Wht are causes of HCC?
A
Hepatitis B and C
Alcohol
NAFL
4
Q
How does cholangiocarcinoma present?
A
Painless jaundice
5
Q
What investifations are done in HCC?
A
50% positive for AFP (check every 6 months in those with fibrosis)
USS/MRI/CT
ERCP for biopsies
6
Q
What is the marker for cholangiocacinoma?
A
CA19-9
7
Q
How is HCC managed
A
Surgical only
Transplant/resection
8
Q
How is cholangiocarcinoma managed?
A
ERCP stenting
Sorafenib prolongs life
