PSC Flashcards
1
Q
What does PSC occur alongside in 70% cases?
A
UC
2
Q
What causes PSC?
A
Autoimmune inflammation of intra or extra hepatic ducts causing strictures and cholestasis and gallstones
3
Q
What are the abs for PSC?
A
None specific
But pANCA, ANA and aCL useful in prognosis
4
Q
How does PSC present?
A
Jaundice RUQ pain Pruritis Fatigue Hepatomegaly
5
Q
What infections/conditions is PSC associated wtih?
A
Acute bacterial cholangitis Cholangiocarcinoma Colorectal cancer Cirrhosis Vitamin deficiency
6
Q
How is PSC diagnosed?
A
MRI and cholangiopancreatography
7
Q
What is seen in LFTs in PSC?
A
ALP up
Increaed Billi
then others follow
8
Q
How is PSC managed?
A
ERCP to dialte strictures and tent
Ursodeoxycholic acid
Cholestyramine
Monitor complications
