Type 2 diabetes management Flashcards
1
Q
What is first line treatment?
A
Metformin
2
Q
How does metformin work?
A
By improving insulin action. Increases receptor function and thus increases glucose uptake
3
Q
Where does metformin work?
A
The liver
4
Q
What is second line treatment?
A
Sulphonylurates
5
Q
Where do sulphonylurates work?
A
The pancreas
6
Q
How do sulphonylurates work?
A
Increases insulin release
7
Q
What is third line treatment?
A
Thiazolidones
8
Q
How do thiazolidiones work?
A
Reduce insulin resistance in liver and peripheral tissues
9
Q
Where do thiazolidiones work?
A
Adipose tissue
