Tumour Pathology 1 Flashcards
What is a tumour and what are some characteristics of it?
A tumour/neoplasm is an abnormal growing mass of tissue. The growth is uncoordinated with that of surrounding tissue.
The growth continues after the stimulus that caused it is removed so it’s an irreversible change.
They can be benign or malignant.
What is a cancer?
A fundamental property of cancer is it’s ability to invade into adjacent tissue and to metastasise and grow at other body sites.
How do you classify tumours and why is it important?
It is important to understand the tumours behaviour and predict outcomes or select therapies.
They’re classified based on tissue of origin and whether benign or malignant.
What are glandular tumours called?
Benign is adenoma.
Malignant is adenocarcinoma.
What are squamous tumours called?
Benign is squamous papilloma.
Malignant is squamous carcinoma.
What are bone tumours called?
Benign is osteoma.
Malignant is osteosarcoma.
What are fibrous tumours called?
Benign is fibroma.
Malignant is fibrosarcoma.
What are lymphoid tissue tumours called?
Lymphomas.
What are melanocyte tumours called?
Benign is naevus.
Malignant is melanoma.
What are CNS tumours called?
Astrocytoma.
What are tumours of the PNS called?
Schwannoma.
What are germ cells tumours called and where do they develop?
Teratomas are tumours found in the ovaries and testes.
Ovarian teratomas are usually benign.
Testicular teratomas are usually malignant.
What are some characteristics of benign tumours?
They have a non invasive growth pattern.
They’re usually encapsulated.
No evidence of invasion and no metastasis.
The cells function similar to normal.
They rarely cause death.
What are some characteristics of malignant tumours?
They have an invasive growth pattern. They have no capsule or the capsule is breached by tumour cells. The cells are abnormal. Loss of normal function. They metastasis. They frequently cause death.
