Genetics

Question 1

What kind of genes are sickle cell and cystic fibrosis genes?

Answer 1

Recessive

Question 2

What autosomal dominant inheritance?

Answer 2

Each child has 50% chance of inheriting the mutation.
No skipped generations.
Equally transmitted by men and women.
Male to male transmission.
Eg achondroplasia or Huntington’s disease

Question 3

What is X linked/ sex linked inheritance?

Answer 3

Only makes affected classically. 
Can skip generations. 
Unaffected women and affected men can transmit condition. 
No male to male transmission. 
Eg duchenne muscular dystrophy

Question 4

How many bonds are between A-T and C-G?

Answer 4

Two

Three

Question 5

What are the two arms of chromosomes called?

Answer 5

P is the small arm.

Q is the larger arm.

Question 6

What is chromatin?

Answer 6

Mixture of DNA, proteins and RNA that package DNA in the nucleus.

Question 7

How is chromatin made more accessible for replication?

Answer 7

Histones being enzymatically modified.

Histones being displaced.

Question 8

What direction does take DNA replication take place?

Answer 8

5’ to 3’

Question 9

When are chromosomes most visible/compact?

Answer 9

Metaphase.