tumour lysis Flashcards

1
Q

aetiology?

A

comes as a result of treatment with chemo

cell lysis leads to release of cell content into blood

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2
Q

presentation ?

A

similar to an acute kidney injury??

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3
Q

what will bloods show?

A

High PO4
High K+
High urate
Low Ca

Acidosis

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4
Q

how to treat TLS?

A

Fluid resus

treat electrolyte abnormalities;

High PO4 - phosphate binders
High K+ - insulin/glucose, ca gluconate
High urate - allopurinol
Low Ca - correct phosphate

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