diabetes cpc Flashcards
what are the measurement parameters for diabetes?
Symptoms plus one of the following
- A fasting plasma glucose > 7 mmol/L
- A 2 hour plasma glucose in a GTT > 11.1 mmol/L
- HbA1c > 6.5% (48 mmol/mol)
Or 2 bloods but no symptoms
what is the BbA1c for a non-diabetic person?
○ Non-diabetic HbA1c < 42 mmol/mol
3 causes of metabolic alkalosis?
H+ loss (e.g. vomiting)
Hypokalaemia - hyopkalaemic alkalosis
Ingestion of Bicarbonate
formula for osmolality?
mmemonic?
im usually 2 nakud but I’m a g:
2 (Na+K) + U + G
formula for anion gap?
Na + K - Cl - Bicarbonate
remember that apart from Na and K, the last 2 are different from the other equation we have to learn.
3 causes of cushings?
Pituitary adenoma
Ectopic ACTH
Adrenal tumour
when ACTH levels are very very high, what is the cause of severe hypokalaemia?
cortisol binding to MR receptor
what is acute tubular necrosis and what is the treatment ?
Acute tubular necrosis is classified as a “renal” (i.e. not pre-renal or post-renal) cause of acute kidney injury.
Diagnosis is made by a FENa (fractional excretion of sodium) > 3% and presence of muddy casts (a type of granular cast) in urinalysis.
Rx: treat underlying cause eg stop drug and rehydrate.
last call - dialysis for 3 weeks
treatment of Diabetic glomerular kidney disease ?
dialysis for life
Cushings showing bilateral adrenal hyperplasia. treatment?
bilateral adrenalectomy
treatment of MI?
STEMI
- PCI aka Primary angioplasty
- within 120 mins
- If PCI not available :
- fibrinolysis (if not contraindicated) : MONA
○ Morphine ○ Aspirin + P2Y12 inhibitor (clopidogrel/ticagrelor) ○ IV GTN - consider this ○ Beta-blocker
- fibrinolysis (if not contraindicated) : MONA
NSTEMI:
If stable -> MONA
If unstable -> Revascularisation (PCI/CABG) + MONA
Hypertonia
Hyperreflexia
Spasticity
Reduced power
poiositve babinsky - remember my baby one
are examples of?
Upper Motor Neurone Signs
Hypotonia/ atonia
Hyporeflexia
Fasciculations
Flacid muscle weakness
are examples of?
Lower Motor Neurone Signs