diabetes cases Flashcards
1
Q
Metformin in overdose can cause ?
A
lactic acidosis
2
Q
why does Metformin cause lactic acidosis?
A
because it inhibits hepatic gluconeogenesis
lactate –> glucose
3
Q
what is the cori cycle?
A
This is the metabolic pathway by which lactate is produced by anaerobic glycolysis in the muscles and moves to the liver to be converted to glucose, which then returns to the muscles and is metabolised back to lactate
4
Q
A2 hour Glucose tolerance test value of 7.8 – 11.1 is indicative of?
A
impaired glucose tolerance
